2. Anti-infection Metabolic Enzyme/Protease
  3. Fungal Bacterial Amylases
  4. Decussatin

Decussatin 是一种 α-Amylases 抑制剂，可从藏药植物川西獐牙菜 (Swertia mussotii) 中分离得到。Decussatin 通过抑制 α-Amylases 的催化活性，减少淀粉等复杂碳水化合物的水解与葡萄糖的肠道吸收，进而降低机体血糖水平。Decussatin 无明显的体外抗菌、抗真菌活性。Decussatin 可用于 2 型糖尿病的研究。

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Decussatin

Decussatin Chemical Structure

CAS No. : 20882-69-3

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Decussatin 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Decussatin is an α-Amylases inhibitor isolated from the Tibetan medicinal plant Swertia mussotii. By inhibiting the catalytic activity of α-Amylases, Decussatin reduces the hydrolysis of complex carbohydrates such as starch and the intestinal absorption of glucose, thereby lowering blood glucose levels in the body. Decussatin shows no significant in vitro antibacterial or antifungal activity. Decussatin can be used for the research of type 2 diabetes[1][2][3].

体外研究
(In Vitro)

Decussatin (8 mg/mL) 在体外抗菌实验中对大肠埃希菌、枯草芽孢杆菌、肺炎克雷伯菌、金黄色葡萄球菌均无明显抑制活性[2]。
Decussatin 在 1 mg/mL 浓度下对 α-淀粉酶的抑制率达 78.0%，该浓度下抑制活性优于同浓度的 Acarbose (HY-B0089)[3]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Decussatin 相关抗体:
体内研究
(In Vivo)

Decussatin 的提取来源植物 Anthocleista vogelii 的水甲醇粗提取物 (1 g/kg；灌胃；每日 1 次；连续 7 天) 可在四氧嘧啶诱导的糖尿病白化 Wistar 大鼠中，显著降低其血糖水平。茎皮提取物可在第 5 天达到 69.68% 的血糖峰值降低率，叶提取物可在第 7 天达 60.35% 的血糖峰值降低率，均高于 Glibenclamide (HY-15206) 的降糖效果[3]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

302.28

Formula

C16H14O6
CAS 号
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Decussatin 相关分类

  • 摩尔计算器

  • 稀释计算器

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Decussatin20882-69-3FungalBacterialAmylasesxanthonen-hexane:ethyl acetate:methanol:waterhigh-speed counter-current chromatographycrude chloroform extractSwertia mussotiiNMR spectroscopyInhibitorinhibitorinhibit

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