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  4. Demethylsalvicanol

Demethylsalvicanol ((+)-Demethylsalvicanol) 是一种二萜类化合物，是一种抗癌剂，对 P388 小鼠白血病细胞的 IC50 为 0.71 μg/mL。Demethylsalvicanol 可诱导白血病细胞和昆虫 Sf9 细胞产生细胞毒活性。Demethylsalvicanol 对 Leptinotarsa decemlineata 具有拒食活性。Demethylsalvicanol 可用于白血病的相关研究。

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Demethylsalvicanol

Demethylsalvicanol Chemical Structure

CAS No. : 124960-41-4

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Demethylsalvicanol 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Demethylsalvicanol ((+)-Demethylsalvicanol), a diterpene, is a anticancer agent with an IC50 of 0.71 μg/mL against P388 murine leukemia cells. Demethylsalvicanol induces cytotoxic activity against leukemia cells and insect Sf9 cells. Demethylsalvicanol acts as an antifeedant against Leptinotarsa decemlineata. Demethylsalvicanol can be used for the research of leukemia[1].

体外研究
(In Vitro)

Demethylsalvicanol (48 h) 对小鼠 P388 白血病细胞表现出细胞毒活性，其 IC50 为 0.71 μg/mL[1]。
Demethylsalvicanol (48 h) 可强效且选择性地抑制草地贪夜蛾 Sf9 昆虫细胞的存活能力，对哺乳动物中国仓鼠卵巢 CHO 细胞无活性[2]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Demethylsalvicanol 相关抗体:
体内研究
(In Vivo)

Demethylsalvicanol 对成年科罗拉多马铃薯甲虫 (Leptinotarsa decemlineata) 表现出中等强度的拒食活性[2]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

318.45

Formula

C20H30O3
CAS 号
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Demethylsalvicanol 相关分类

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Demethylsalvicanol124960-41-4(+)-DemethylsalvicanolDrug DerivativeDrug derivativeSpodoptera frugiperdaSpodoptera littoralisLeptinotarsa decemlineataleukemia cellsleukemiaChinese hamster ovary CHO cellsSalvia broussonetiiP388 murine leukemia cellsSf9 cellsPerovskia abrotanoidesInhibitorinhibitorinhibit

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