2. Anti-infection
  3. Bacterial
  4. Dimethoxane

Dimethoxane 是一种抗菌 (antibacterial) 剂，也是一种具有口服活性的致癌剂。Dimethoxane 对多种细菌发挥缓慢的杀菌作用、可阻止细菌生长的快速抑菌作用，且不会诱导细菌裂解。Dimethoxane 可诱导大鼠多肿瘤形成。Dimethoxane 在化妆品配方中用作低毒防腐剂，可控制水基体系、乳剂和混悬液中的腐败微生物。

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Dimethoxane

Dimethoxane Chemical Structure

CAS No. : 828-00-2

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Dimethoxane 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Dimethoxane is an antibacterial agent and an orally active oncogen. Dimethoxane exerts slow bactericidal action against various bacteria, rapid bacteriostatic action that halts bacterial growth, and does not induce bacterial lysis. Dimethoxane induces multiple tumor formation in rats. Dimethoxane functions as a low-toxicity preservative in cosmetic formulations and controls spoilage microorganisms in aqueous systems, emulsions, and suspensions[1][2].

体外研究
(In Vitro)

Dimethoxane 在肉汤连续稀释试验中对铜绿假单胞菌 NCTC 6750 的最低抑菌浓度为 500 μg/cm3，对大肠杆菌 15TAU NCIB 10430 的最低抑菌浓度为 750 μg/cm3，对金黄色葡萄球菌 NCTC 6571 的最低抑菌浓度为 1000 μg/cm3[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Dimethoxane 相关抗体:
体内研究
(In Vivo)

Dimethoxane (饮用水中 1% 溶液；口服；连续给药；613 天) 可使雄性 Wistar 大鼠的肿瘤发生率达到 56% (25 只大鼠中出现 14 个肿瘤)，诱发的肿瘤包括肝细胞瘤、肾癌、皮肤及皮下肉瘤/癌、淋巴肉瘤和白血病[2]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Wistar (young-adult male, 120-180 g)[2]
Dosage: 1% solution in drinking water; average total dose 237 g
Administration: oral; continuous; 613 days
Result: Detected 14 total tumors among 25 treated rats.
Induced 8 hepatomas, 1 papillary transitional cell carcinoma of the kidney, 2 skin and subcutaneous tumors, 2 lymphosarcomas, and 1 myelogenous leukemia.
Caused death in 5 rats, 4 of which had tumors.
Observed hepatomas with numerous small foci, including one undifferentiated tumor over 3 cm in diameter; kidney tumor measuring 5.3 cm; skin epidermoid carcinoma measuring 2 cm; subcutaneous fibrosarcoma measuring 6 cm; mediastinal lymphosarcoma measuring 1.0 × 0.5 cm; and submandibular lymphosarcoma measuring 8 × 6 × 4 cm.
分子量

174.20

Formula

C8H14O4
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Dimethoxane 相关分类

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  • 稀释计算器

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Keywords:

Dimethoxane828-00-2BacterialEscherichia coli 15TAU NCIB 10430lymphosarcomahepatomasepidermoid carcinoma of the skinpapillary transitional cell carcinoma of the kidneymyelogenous leukemiamale Wistar ratssubcutaneous fibrosarcomaStaphylococcus aureus NCTC 6571Pseudomonas aeruginosa NCTC 6750Inhibitorinhibitorinhibit

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