1. Immunology/Inflammation NF-κB Metabolic Enzyme/Protease
  2. Reactive Oxygen Species (ROS)
  3. Dimethyl lithospermate

Dimethyl lithospermate 是一种抗氧化剂。Dimethyl lithospermate 可清除 DPPH 自由基和抑制自由基生成。Dimethyl lithospermate 也可保护肝细胞免受叔丁基过氧化氢 (t-BHP) 诱导的氧化损伤。Dimethyl lithospermate 可用于氧化损伤相关研究。

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Dimethyl lithospermate

Dimethyl lithospermate Chemical Structure

CAS No. : 54844-34-7

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Dimethyl lithospermate is an antioxidant. Dimethyl lithospermate scavenges DPPH free radicals and inhibits free radical generation. Dimethyl lithospermate also protects hepatocytes from tert-butyl hydroperoxide (t-BHP)-induced oxidative damage. Dimethyl lithospermate can be used in oxidative damage-related research[1].

体外研究
(In Vitro)

Dimethyl lithospermate (2-50 μM; 30 min) 可剂量依赖性地抑制 AC2F 肝细胞中的自由基生成[1]
Dimethyl lithospermate (2-50 μM; 1 h) 呈剂量依赖性地保护 AC2F 肝细胞免受 t-BHP 诱导的损伤[1]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Viability Assay[1]

Cell Line: AC2F liver cells
Concentration: 2 μM, 10 μM, 50 μM
Incubation Time: 1 h
Result: Increased viable cell number to 133.49 at 2 μM. (control group viable cell number: 100)
Increased viable cell number to 168.88 at 10 μM.
Increased viable cell number to 171.73 at 50 μM.
分子量

566.51

Formula

C29H26O12

CAS 号
中文名称

紫草酸二甲酯

结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Dimethyl lithospermate
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