1. 疾病领域
  2. 癌症 泌尿生殖系统疾病
  3. 卵巢癌 泌尿生殖系统癌症
  4. DK-139

DK-139 是一种带有肉桂醛骨架的多酚类化合物。DK-139 可抑制耐 Cisplatin (HY-17394) 的人卵巢癌细胞的克隆形成生长。DK-139 可用于顺铂耐药型卵巢癌的相关研究。

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DK-139

DK-139 Chemical Structure

CAS No. : 1426059-23-5

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

DK-139 is a polyphenol compound bearing a cinnamaldehyde scaffol. DK-139 inhibits clonogenic growth of Cisplatin (HY-17394)-resistant human ovarian cancer. DK-139 can be used for the research of cisplatin-resistant ovarian cancer[1].

体外研究
(In Vitro)

DK-139 (Compound 17) (5-20 μM; 7 days) 可抑制 Cisplatin (HY-17394) 耐药人卵巢癌 A2780/Cis 细胞的克隆形成能力,其 GI50 为 11.30 μM[1]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Proliferation Assay[1]

Cell Line: Cisplatin-resistant human ovarian cancer A2780/Cis cells
Concentration: 5, 10, 20 μM
Incubation Time: 7 days
Result: Exhibited a half-maximal cell growth inhibitory concentration (GI50) of 11.30 μM.
分子量

314.33

Formula

C18H18O5

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

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参考文献
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
DK-139
目录号:
HY-116562
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