2. Immunology/Inflammation NF-κB Metabolic Enzyme/Protease GPCR/G Protein
  3. Reactive Oxygen Species (ROS) Interleukin Related Prostaglandin Receptor
  4. (E/Z)-3-Hydroxylicochalcone A

(E/Z)-3-Hydroxylicochalcone A (Compound 1) 是一种被发现存在于甘草 (Glycyrrhiza inflata 和 Glycyrrhiza uralensis) 中的黄酮类化合物，具有抗氧化和抗炎活性。(E/Z)-3-Hydroxylicochalcone A 可抑制大鼠肝微粒体中的脂质过氧化反应。(E/Z)-3-Hydroxylicochalcone A 可抑制 LPS (HY-D1056) 诱导的活性氧 (ROS)、NO、IL-6 及 PGE2 的产生。

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(E/Z)-3-Hydroxylicochalcone A

(E/Z)-3-Hydroxylicochalcone A Chemical Structure

CAS No. : 1083200-74-1

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(E/Z)-3-Hydroxylicochalcone A 相关抗体

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

(E/Z)-3-Hydroxylicochalcone A (Compound 1) is a flavonoid found in licorice (Glycyrrhiza inflata and
Glycyrrhiza uralensis), with antioxidant and anti-inflammatory activity. (E/Z)-3-Hydroxylicochalcone A inhibits lipid peroxidation in rat liver microsomes. (E/Z)-3-Hydroxylicochalcone A inhibits LPS (HY-D1056)-induced ROS, NO, IL-6, and PGE2 production[1].

IC50 & Target[1]

IL-6

 

体外研究
(In Vitro)

(E/Z)-3-Hydroxylicochalcone A (Compound DTM) 可抑制大鼠肝微粒体中的脂质过氧化，其 EC50 为 9.22 μM[1]。
(E/Z)-3-Hydroxylicochalcone A (1-10 μM; 24 h) 可抑制 LPS (HY-D1056) 诱导的 RAW 264.7 细胞中 ROS 生成以及 NO、IL-6 和 PGE2 的水平[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

(E/Z)-3-Hydroxylicochalcone A 相关抗体:
分子量

354.40

Formula

C21H22O5
CAS 号
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

(E/Z)-3-Hydroxylicochalcone A 相关分类

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Keywords:

(E/Z)-3-Hydroxylicochalcone A1083200-74-1Reactive Oxygen Species (ROS)Interleukin RelatedProstaglandin ReceptorILGlycyrrhiza inflataanti-inflammatory activityreactive oxygen speciesrat liver microsomesinterleukin-6macrophagesGlycyrrhiza uralensisantioxidant activitylipid peroxidationnitric oxideInhibitorinhibitorinhibit

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