2. Others Immunology/Inflammation
  3. Reference Standards Complement System
  4. EG00229 trifluoroacetate (Standard)

EG00229 trifluoroacetate (Standard) 是 EG00229 (trifluoroacetate) (HY-10799) 的分析标准品。本产品用于研究及分析应用。EG00229 是一种神经纤维蛋白 1 受体 (NRP1) 拮抗剂。EG00229 选择性抑制 VEGF-A 与 NRP1 b1 域的结合， IC50 为 3μM，但对 VEGFA 与 VEGFR-1 和 VEGFR-2 的结合没有影响。

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EG00229 trifluoroacetate (Standard)

EG00229 trifluoroacetate (Standard) Chemical Structure

CAS No. : 1210945-69-9

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EG00229 trifluoroacetate (Standard) 相关抗体

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生物活性

EG00229 trifluoroacetate (Standard) is the analytical standard of EG00229 (trifluoroacetate) (HY-10799). This product is intended for research and analytical applications. EG00229 is a neuropilin 1 (NRP1) receptor antagonist. EG00229 selectively inhibits VEGF-A binding to NRP1 b1 domain with an IC50 of 3 μM, but has no effect on VEGFA binding to VEGFR-1 and VEGFR-2[1].

IC50 & Target

IC50: 8 μM (125I-VEGF-A binding to PAE/NRP1); 3 μM (bt-VEGF-A binding to purified NRP1 b1 domain)[1].
分子量

611.60

Formula

C19H20F3N7O7S3
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

EG00229 trifluoroacetate (Standard) 相关分类

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Keywords:

EG00229 trifluoroacetate (Standard)1210945-69-9Reference StandardsComplement SystemInhibitorinhibitorinhibit

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