1. Cell Cycle/DNA Damage Immunology/Inflammation
  2. Folate Receptor (FR) CD3
  3. Eliroptamig

Eliroptamig 是一种靶向白蛋白 (Albumin)、叶酸受体 α (FOLR1) 和 分化簇 3 (CD3) 的多特异性抗体。Eliroptamig 通过结合白蛋白延长半衰期,同时靶向肿瘤细胞的 FOLR1 并激活 T 细胞,实现对肿瘤的精准杀伤。

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Eliroptamig

Eliroptamig Chemical Structure

CAS No. : 3064817-30-4

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查看 Folate Receptor (FR) 亚型特异性产品:

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Eliroptamig is a multispecific antibody targeting albumin, folate receptor α (FOLR1) and cluster of differentiation 3 (CD3). Eliroptamig extends its half-life by binding to albumin, while targeting FOLR1 on tumor cells and activating T cells to achieve precise tumor killing[1].

同型

immunoglobulin (VH-prodomain-scFvhl-L-kappa)_VH-G1(CH1-h5)

反应种属

Human

基因 ID

916  [NCBI] & 2346  [NCBI] & 704892  [NCBI]

Accession
靶点

CD3E & FOLH1 & ALB

应用

ELISA, FACS, Functional assay

偶联物

Unconjugated

复溶方法

The product can be reconstituted/diluted with sterile PBS or saline.

CAS 号
组分

Please refer to the lot-specific COA for specific buffer information.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Eliroptamig
目录号:
HY-P992112
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