2. Metabolic Enzyme/Protease
  3. Phosphodiesterase (PDE)
  4. Enpp-1-IN-29

Enpp-1-IN-29 (Compound 1) 是一种高度选择性的胞外核苷酸焦磷酸酶/磷酸二酯酶 1 (ENPP1) 抑制剂 (IC50=0.05 nM)。Enpp-1-IN-29 有望用于 ENPP1 过度表达的癌症 (例如乳腺癌、头颈癌、转移性染色体不稳定肿瘤) 以及免疫相关疾病 (例如自身免疫性疾病、肿瘤免疫逃逸) 的研究。

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Enpp-1-IN-29

Enpp-1-IN-29 Chemical Structure

CAS No. : 2944114-41-2

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Enpp-1-IN-29 相关抗体

Top Publications Citing Use of Products

查看 Phosphodiesterase (PDE) 亚型特异性产品:

查看所有亚型
PDE1 PDE2 PDE3 PDE4 PDE5 PDE6 PDE7 PDE9 PDE10 PDE11 PDE12 PDE8 Autotaxin

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Enpp-1-IN-29 (Compound 1) is a highly selective ectonucleotide pyrophosphatase/phosphodiesterase 1 (ENPP1) inhibitor (IC50=0.05 nM). Enpp-1-IN-29 is promising for research of ENPP1-overexpressing cancers (e.g., breast cancer, head/neck cancer, metastatic chromosome-unstable tumors) and immune-related diseases (e.g., autoimmune disorders, tumor immune evasion)[1].

分子量

436.39

Formula

C18H14F2N4O5S
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Enpp-1-IN-29 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Enpp-1-IN-292944114-41-2Phosphodiesterase (PDE)ENPP1cancersimmune-related diseasesInhibitorinhibitorinhibit

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目录号：
HY-176874
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