2. Cell Cycle/DNA Damage
  3. DNA/RNA Synthesis
  4. Epidermal mitosis inhibiting pentapeptide

Epidermal mitosis inhibiting pentapeptide，一种五肽，是一种生理性的表皮细胞增殖抑制剂。Epidermal mitosis inhibiting pentapeptide 能够显著降低表皮角质形成细胞的 DNA 合成速率和有丝分裂率。Epidermal mitosis inhibiting pentapeptide 在皮肤癌发生模型中度地增强了皮肤肿瘤的发生，但又显示出更高的促进已形成肿瘤消退的趋势。Epidermal mitosis inhibiting pentapeptide 可被是血管紧张素转换酶 (ACE) 水解。Epidermal mitosis inhibiting pentapeptide 可用于癌症过程研究。

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Epidermal mitosis inhibiting pentapeptide

Epidermal mitosis inhibiting pentapeptide Chemical Structure

CAS No. : 106678-69-7

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Epidermal mitosis inhibiting pentapeptide 相关抗体

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生物活性

Epidermal mitosis inhibiting pentapeptide is a five-peptide that acts as a physiological inhibitor of epidermal cell proliferation. This pentapeptide can significantly reduce the DNA synthesis rate and mitotic rate of epidermal keratinocytes. Epidermal mitosis inhibiting pentapeptide moderately enhances the occurrence of skin tumors in skin cancer models, but also shows a higher tendency to promote the regression of already formed tumors. Epidermal mitosis inhibiting pentapeptide can be hydrolyzed by angiotensin-converting enzyme (ACE). Epidermal mitosis inhibiting pentapeptide can be used in cancer process research[1][2].

分子量

517.44

Formula

C19H27N5O12
CAS 号
Sequence

{pGlu}-Glu-Asp-Ser-Gly
Sequence Shortening

{pGlu}-EDSG
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Epidermal mitosis inhibiting pentapeptide 相关分类

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Keywords:

Epidermal mitosis inhibiting pentapeptide106678-69-7DNA/RNA Synthesistwo-stage carcinogenesistumor promotionTPAhairless micecell cycletumor enhancementtumor regressionInhibitorinhibitorinhibit

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