1. 疾病领域
  2. 血液和心脑血管疾病
  3. 心血管疾病
  4. 高血压
  5. Flavodilol

Flavodilol 是一种口服有效的抗高血压剂。Flavodilol 可显著降低正常血压和自发性高血压大鼠 (SHR) 心脏组织中的儿茶酚胺和 5- 羟色胺水平。Flavodilol 可用于高血压研究。

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Flavodilol

Flavodilol Chemical Structure

CAS No. : 79619-31-1

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Customer Review

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Flavodilol is an orally active antihypertensive agent. Flavodilol extensively depletes catecholamines and serotonin in heart tissue of normotensive and spontaneously hypertensive rats (SHR). Flavodilol can be used for hypertension research[1].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
DU-145 IC50
17.1 μM
Compound: 11
Antiproliferative activity against human DU-145 cells assessed as inhibition of cell proliferation incubated for 72 hrs by WST assay
Antiproliferative activity against human DU-145 cells assessed as inhibition of cell proliferation incubated for 72 hrs by WST assay
[PMID: 36493620]
HCT-15 IC50
21.38 μM
Compound: 11
Antiproliferative activity against human HCT-15 cells assessed as inhibition of cell proliferation incubated for 72 hrs by WST assay
Antiproliferative activity against human HCT-15 cells assessed as inhibition of cell proliferation incubated for 72 hrs by WST assay
[PMID: 36493620]
T47D IC50
4.85 μM
Compound: 11
Antiproliferative activity against human T47D cells assessed as inhibition of cell proliferation incubated for 72 hrs by WST assay
Antiproliferative activity against human T47D cells assessed as inhibition of cell proliferation incubated for 72 hrs by WST assay
[PMID: 36493620]
分子量

353.41

Formula

C21H23NO4

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Flavodilol
目录号:
HY-105527
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