Flusulfamide  (Synonyms: 磺菌胺)

Flusulfamide is a sulfonanilide Fungicide that effectively inhibits the germination of resting spores of Plasmodiophora brassicae, the pathogen causing clubroot in cruciferous crops. Flusulfamide blocks the developmental process of resting spores from stage 1 to stage 2. By downregulating germination-related genes and upregulating immunophilin genes (such as PbCyp3), it induces abnormal accumulation of the PbCYP3 protein, thereby causing the spores to deplete energy in a state of continuous energy consumption without germination, and reducing their infectivity. Flusulfamide reduces soil ATP content in the early stage of application, but soil microbial biomass gradually recovers 3 days later. Flusulfamide is widely used in research on clubroot control^[1][2][3].

Flusulfamide (1 ppm; 3-6 d) 可在孵育后第 3 天和第 6 天抑制 Plasmodiophora brassicae (Williams 生理小种 4) 休眠孢子中初级游动孢子发生从 1 期向 2 期和 3 期的进程^[3]。
Flusulfamide (0.5-2 ppm; 5 d) 可下调 Plasmodiophora brassicae (Williams 生理小种 4) 休眠孢子中 80% 可重复表达的萌发相关基因^[3]。
Flusulfamide (1 ppm; 24 h) 可显著上调 Plasmodiophora brassicae (Williams 致病型 4) 休眠孢子中大多数亲免素基因的表达，其中 PbCYP3、PbCYP8 和 PbCYP10 在截至 24 小时的多个早期时间点均呈现表达上调^[3]。
Flusulfamide (1 ppm; 24 h) 可诱导 Plasmodiophora brassicae (Williams’ 生理小种 4) 休眠孢子中 17.5 kDa PbCYP3 蛋白的积累量增加^[3]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

415.17

C₁₃H₇Cl₂F₃N₂O₄S

106917-52-6

磺菌胺

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Aviantara D B. The effects of fluazinam and flusulfamide on soil ATP microbial biomass[C]//Proceeding of the International Seminar on Chemistry 2008. 2008: 269-272.

  [2]. Ahn, Gyeong-geun, et al. Analytical Method for the Residues of Flusulfamide, a Benzenesulfonamide Fungicide, in Major Agricultural Products [J]. Korean J. Environ. Agric., 2018, 37(1): 57-65.

  [3]. Sasaki T, et al. Effects of flusulfamide on spore germination of Plasmodiophora brassicae[J]. Journal of Pesticide Science, 2024, 49(1): 52-57.