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  3. Biochemical Assay Reagents
  4. Fmoc-PNA-A(Bhoc)-OH

Fmoc-PNA-A(Bhoc)-OH 是一种带有腺嘌呤碱基的保护型肽核酸 (PNA) 单体。Fmoc-PNA-A(Bhoc)-OH 含有 Fmoc 和二苯甲氧基羰基 (Bhoc) 保护基团，是专为固相 PNA 合成设计的标准构建模块。Fmoc-PNA-A(Bhoc)-OH 能够高效地用于合成基于 PNA 的序列特异性杂交探针。这些探针在分子生物学研究中具有广泛应用，例如可用于表达 HER2 的肿瘤相关研究，为疾病诊断与机制探索提供工具。

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Custom Peptide Synthesis

Fmoc-PNA-A(Bhoc)-OH

Fmoc-PNA-A(Bhoc)-OH Chemical Structure

CAS No. : 186046-82-2

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规格 价格 是否有货 数量
100 mg ￥350
In-stock
250 mg ￥770
In-stock
500 mg ￥1260
In-stock
1 g ￥2030
In-stock
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10 g   询价  

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Fmoc-PNA-A(Bhoc)-OH 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Fmoc-PNA-A(Bhoc)-OH is a protected peptide nucleic acid (PNA) monomer carrying an adenine base. Fmoc-PNA-A(Bhoc)-OH contains Fmoc and benzhydryloxycarbonyl (Bhoc) protecting groups, and serves as a standard building block designed specifically for solid-phase PNA synthesis. Fmoc-PNA-A(Bhoc)-OH can be efficiently used to synthesize PNA-based sequence-specific hybridization probes. These probes have broad applications in molecular biology research; for example, they can be used in HER2-expressing tumor-related studies, providing tools for disease diagnosis and mechanism exploration[1][2][3].
体外研究
(In Vitro)

Fmoc-PNA-A(Bhoc)-OH (165-331 μM; 2 h) 可生成腺嘌呤 PNA 六聚体 A6，产率为 54%，纯度达 97.4%[1]。
Fmoc-PNA-A(Bhoc)-OH (344 μM; 2 h) 可生成腺嘌呤 PNA 单体 mA，产率为 48%，纯度为 72%[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Fmoc-PNA-A(Bhoc)-OH 相关抗体:
体内研究
(In Vivo)

125I- 与 111In-标记的 Fmoc-PNA-A(Bhoc)-OH 在正常 NMRI 小鼠体内注射后，在 4 小时内表现出极快的血液清除速度，且肾脏摄取量低并呈下降趋势[3]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

725.75

Formula

C40H35N7O7
CAS 号
性状

固体

运输条件

Room temperature in continental US; may vary elsewhere.
储存方式
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
纯度 & 产品资料
参考文献

Fmoc-PNA-A(Bhoc)-OH 相关分类

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  • Do most proteins show cross-species activity?

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Keywords:

Fmoc-PNA-A(Bhoc)-OH186046-82-2Biochemical Assay Reagentssolid-phase synthesisadenine PNA monomer mAher2-expressing tumorsadenine baseZ_HER2:342-SRNMRI micepeptide nucleic acid monomeradenine PNA hexamer A6peptide nucleic acid synthesisPNA-based hybridization probesInhibitorinhibitorinhibit

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