2. Garsevil

Garsevil (LSL 60101) 是一种双相性的、选择性的咪唑啉 I2 受体 (I2-IR) 配体，对高亲和力位点的 pKi 为 9.03，Ki 为 0.9 nM；对低亲和力位点的 pKi 为 5.25，Ki 为 5.6 nM。Garsevil 可用于阿尔茨海默病的相关研究。

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Garsevil

Garsevil Chemical Structure

CAS No. : 150985-54-9

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Garsevil 相关抗体

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  • 生物活性

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生物活性

Garsevil (LSL 60101) is a biphasic, selective imidazoline I2 receptor (I2-IR) ligand, with a pKi of 9.03 and a Ki of 0.9 nM at the high-affinity site, and a pKi of 5.25 and a Ki of 5.6 nM at the low-affinity site. Garsevil is applicable to research related to Alzheimer's disease[1].

体外研究
(In Vitro)

Garsevil 对 I₂-IR 相对于 α₂-肾上腺素能受体 (α₂-AR) 表现出良好的选择性，其 I₂/α₂ 选择性比率为 7244。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Garsevil 相关抗体:
分子量

184.20

Formula

C11H8N2O
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

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  • Do most proteins show cross-species activity?

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Keywords:

Garsevil150985-54-9LSL 60101LSL60101LSL-60101neuroinflammatory gene expressionα2-adrenergic receptorsalzheimer’s diseaseadult Sprague-Dawley ratshuman I2-IRimidazoline I2 receptorhuman prefrontal cortex I2-imidazoline receptorshippocampal FADD protein5-month-old female 5xFAD miceadult CD-1 miceInhibitorinhibitorinhibit

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