2. Gene
  3. Mylk - myosin, light polypeptide kinase Gene

Mylk - myosin, light polypeptide kinase Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: KRP; Mlck; nmMlck; smMLCK; MLCK108; MLCK210; 9530072E15Rik; A930019C19Rik

基因 ID: 107589 | 基因类型: protein coding

关于 Mylk

功能概要

Enables enzyme binding activity. Involved in tonic smooth muscle contraction. Acts upstream of or within cellular response to calcium ion; cellular response to potassium ion; and cellular response to xenobiotic stimulus. Located in cell-cell junction. Is expressed in several structures, including central nervous system; heart; liver; and retina. Human ortholog(s) of this gene implicated in adult respiratory distress syndrome; asthma; and thoracic aortic aneurysm. Orthologous to human MYLK (Myosin light chain kinase). [provided by Alliance of Genome Resources, Apr 2022]

Mylk 基因产物(4)

mRNA Protein Name
NM_001408261.1 NP_001395190.1 myosin light chain kinase, smooth muscle isoform 1
NM_001408262.1 NP_001395191.1 myosin light chain kinase, smooth muscle isoform 3
NM_001408263.1 NP_001395192.1 myosin light chain kinase, smooth muscle isoform 4
NM_139300.4 NP_647461.3 myosin light chain kinase, smooth muscle isoform 2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables enzyme binding IPI
IPI: 通过物理相互作用推断
21074048 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
15102471 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within cellular response to calcium ion IDA
IDA: 通过直接分析推断
18524939 MGI
acts upstream of or within cellular response to potassium ion IDA
IDA: 通过直接分析推断
18524939 MGI
acts upstream of or within cellular response to xenobiotic stimulus IDA
IDA: 通过直接分析推断
18524939 MGI
involved in neurotransmitter receptor transport to postsynaptic membrane IDA
IDA: 通过直接分析推断
26330558 MGI
involved in smooth muscle contraction IMP
IMP: 通过突变表型推断
18586037 MGI
involved in tonic smooth muscle contraction IMP
IMP: 通过突变表型推断
20018858 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cell-cell junction IDA
IDA: 通过直接分析推断
23793062 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

myosin light chain kinase, smooth muscle

kinase-related protein

telokin

相关产品

Pre-clinical Phase
生物活性分子 (11)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-176882 ASK1-IN-11 Inhibitor / 否
HY-RS08923 MYLK Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS08924 MYLK2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS08925 MYLK3 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS08926 MYLK4 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS18624 Mylk Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS22661 Mylk3 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS22662 Mylk4 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS25110 Mylk Rat Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS29175 Mylk3 Rat Pre-designed siRNA Set A / 否
HY-RS29176 Mylk4 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Mylk NCBI NCBI:4638
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