2. Gene
  3. Tmbim6 - transmembrane BAX inhibitor motif containing 6 Gene

Tmbim6 - transmembrane BAX inhibitor motif containing 6 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Bi1; Tegt; 5031406P05Rik

基因 ID: 110213 | 基因类型: protein coding

关于 Tmbim6

功能概要

Enables endoribonuclease inhibitor activity and enzyme binding activity. Involved in cellular response to unfolded protein; negative regulation of RNA metabolic process; and negative regulation of immunoglobulin production. Acts upstream of or within endoplasmic reticulum calcium ion homeostasis; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress; and negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway. Predicted to be located in endoplasmic reticulum membrane and mitochondrial membrane. Is expressed in head and retina. Orthologous to human TMBIM6 (transmembrane Bax Inhibitor motif containing 6). [provided by Alliance of Genome Resources, Apr 2022]

Tmbim6 基因产物(4)

mRNA Protein Name
NM_001171034.1 NP_001164505.1 bax inhibitor 1
NM_001171035.1 NP_001164506.1 bax inhibitor 1
NM_001171036.1 NP_001164507.1 bax inhibitor 1
NM_026669.4 NP_080945.1 bax inhibitor 1
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables endoribonuclease inhibitor activity IMP
IMP: 通过突变表型推断
19328063 MGI
enables enzyme binding IPI
IPI: 通过物理相互作用推断
19328063 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to unfolded protein IMP
IMP: 通过突变表型推断
19328063 MGI
acts upstream of or within endoplasmic reticulum calcium ion homeostasis IDA
IDA: 通过直接分析推断
15304216 MGI
acts upstream of or within intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress IDA
IDA: 通过直接分析推断
15304216 MGI
acts upstream of or within intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress IMP
IMP: 通过突变表型推断
15304216 MGI
involved in negative regulation of RNA splicing IMP
IMP: 通过突变表型推断
19328063 MGI
acts upstream of or within negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway IGI
IGI: 通过遗传相互作用推断
22240901 MGI
involved in negative regulation of endoribonuclease activity IMP
IMP: 通过突变表型推断
19328063 MGI
involved in negative regulation of immunoglobulin production IMP
IMP: 通过突变表型推断
19328063 MGI
acts upstream of or within neuron intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress IMP
IMP: 通过突变表型推断
15304216 MGI
involved in response to endoplasmic reticulum stress IMP
IMP: 通过突变表型推断
21075086 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

bax inhibitor 1

BI-1

testis enhanced gene transcript

testis-enhanced gene transcript protein

transmembrane BAX inhibitor motif-containing protein 6

相关产品

Pre-clinical Phase
生物活性分子 (5)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-137175 TMBIM6 antagonist-1 Antagonist 98.92% 否
HY-161388 NSCLC-IN-1 Inducer / 否
HY-RS14620 TMBIM6 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS19822 Tmbim6 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS26318 Tmbim6 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Tmbim6 NCBI NCBI:7009
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