2. Gene
  3. Pde6c - phosphodiesterase 6C, cGMP specific, cone, alpha prime Gene

Pde6c - phosphodiesterase 6C, cGMP specific, cone, alpha prime Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: cpfl1

基因 ID: 110855 | 基因类型: protein coding

关于 Pde6c

功能概要

Predicted to enable 3',5'-cyclic-nucleotide phosphodiesterase activity. Acts upstream of or within phototransduction, visible light; retinal cone cell development; and visual perception. Predicted to be located in plasma membrane. Is expressed in brain and retina. Used to study achromatopsia. Human ortholog(s) of this gene implicated in cone-rod dystrophy. Orthologous to human PDE6C (phosphodiesterase 6C). [provided by Alliance of Genome Resources, Apr 2022]

Pde6c 基因产物(2)

mRNA Protein Name
NM_001170959.1 NP_001164430.1 cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha' isoform 2
NM_033614.2 NP_291092.1 cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha' isoform 1
基因本体论
  • 生物过程
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within phototransduction, visible light IMP
IMP: 通过突变表型推断
16723493 MGI
acts upstream of or within retinal cone cell development IMP
IMP: 通过突变表型推断
21052544 MGI
acts upstream of or within sensory perception of light stimulus IMP
IMP: 通过突变表型推断
16723493 MGI
acts upstream of or within visual perception IMP
IMP: 通过突变表型推断
22937111 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha'

cGMP phosphodiesterase 6C

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS10234 PDE6C Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS21685 Pde6c Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS28203 Pde6c Rat Pre-designed siRNA Set A Pre-designed Set / 否
HY-112704 PDE5-IN-2 Inhibitor / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Pde6c NCBI NCBI:5146
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