2. Gene
  3. ADAM29 - ADAM metallopeptidase domain 29 Gene

ADAM29 - ADAM metallopeptidase domain 29 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：ADAM 金属肽酶结构域 29

种属: Homo sapiens

同用名: CT73; svph1

基因 ID: 11086 | 基因类型: protein coding

关于 ADAM29

Cytogenetic location: 4q34.1 Genomic coordinates (GRCh38): 4:174,918,358-174,978,180 (from NCBI)

This gene has 14 transcripts (splice variants), 416 orthologues and 20 paralogues. Restricted expression toward testis (RPKM 20.8).

功能概要

该基因编码 ADAM (一种去整合素和金属蛋白酶结构域) 家族的成员。该家族的成员是膜锚定蛋白，在结构上与蛇毒解离蛋白相关，并且涉及涉及细胞-细胞和细胞-基质相互作用的各种生物过程，包括受精、肌肉发育和神经发生。该基因编码的蛋白质在睾丸中高表达，可能参与人类精子发生。可变剪接导致编码相同蛋白质的多个转录变体。[RefSeq 提供，2008 年 7 月]

This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene is highly expressed in testis and may be involved in human spermatogenesis. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Jul 2008]

ADAM29 基因产物(7)

mRNA Protein Name
NM_001130703.1 NP_001124175.1 disintegrin and metalloproteinase domain-containing protein 29 preproprotein
NM_001130704.1 NP_001124176.1 disintegrin and metalloproteinase domain-containing protein 29 preproprotein
NM_001130705.1 NP_001124177.1 disintegrin and metalloproteinase domain-containing protein 29 preproprotein
NM_001278125.1 NP_001265054.1 disintegrin and metalloproteinase domain-containing protein 29 preproprotein
NM_001278126.1 NP_001265055.1 disintegrin and metalloproteinase domain-containing protein 29 preproprotein
NM_001278127.1 NP_001265056.1 disintegrin and metalloproteinase domain-containing protein 29 preproprotein
NM_014269.4 NP_055084.3 disintegrin and metalloproteinase domain-containing protein 29 preproprotein

ADAM29 蛋白结构

Pep_M12B_propep

Pep_M12B_propep: Reprolysin family propeptide (32 - 150)

Reprolysin

Reprolysin: Reprolysin (M12B) family zinc metalloprotease (198 - 387)

Disintegrin

Disintegrin: Disintegrin (406 - 480)

ADAM_CR

ADAM_CR: ADAM cysteine-rich (483 - 598)

  • 0
  • 200
  • 400
  • 600
  • 820 a.a.
蛋白主名 其他名称

disintegrin and metalloproteinase domain-containing protein 29

a disintegrin and metalloproteinase domain 29

关联疾病

疾病名称 别名
Melanoma

Malignant Melanoma

Cutaneous Melanoma

Naevocarcinoma

Malignant Melanomas
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (2)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS00281 ADAM29 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS20133 Adam29 Mouse Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Canis familiaris ADAM29 VGNC VGNC:37583
Rattus norvegicus ADAM29 RGD RGD:1309066
Mus musculus ADAM29 MGD MGI:2676326
Macaca mulatta ADAM29 VGNC VGNC:106537
Others ADAM29 NCBI
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