2. Gene
  3. GLCCI1 - glucocorticoid induced 1 Gene

GLCCI1 - glucocorticoid induced 1 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：糖皮质激素诱导 1

种属: Homo sapiens

同用名: GCTR; GIG18; TSSN1; FAM117C

基因 ID: 113263 | 基因类型: protein coding

关于 GLCCI1

Cytogenetic location: 7p21.3 Genomic coordinates (GRCh38): 7:7,968,796-8,089,080 (from NCBI)

This gene has 12 transcripts (splice variants), 271 orthologues, 2 paralogues and is associated with 1 phenotype. Broad expression in thyroid (RPKM 12.0), testis (RPKM 9.8) and 24 other tissues.

功能概要

该基因编码一种功能未知的蛋白质。该基因的表达由糖皮质激素诱导，可能是糖皮质激素诱导的细胞凋亡的早期标志物。该基因中的单核苷酸多态性与哮喘患者吸入糖皮质激素的反应降低有关。[RefSeq 提供，2012 年 2 月]

This gene encodes a protein of unknown function. Expression of this gene is induced by glucocorticoids and may be an early marker for glucocorticoid-induced Apoptosis. Single nucleotide polymorphisms in this gene are associated with a decreased response to inhaled glucocorticoids in asthmatic patients. [provided by RefSeq, Feb 2012]

GLCCI1 基因产物(1)

mRNA Protein Name
NM_138426.4 NP_612435.1 glucocorticoid-induced transcript 1 protein
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
28514442 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

GLCCI1 蛋白结构

FAM117

FAM117: Protein Family FAM117 (167 - 480)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 500
  • 547 a.a.
蛋白主名 其他名称

glucocorticoid-induced transcript 1 protein

glucocorticoid induced transcript 1

关联疾病

疾病名称 别名
Glucocorticoid Therapy, Response To

GCTR
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS05466 GLCCI1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS21857 Glcci1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS28374 Glcci1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Mus musculus GLCCI1 MGD MGI:2179717
Canis familiaris GLCCI1 VGNC VGNC:54307
Felis catus GLCCI1 VGNC VGNC:102586
Bos taurus GLCCI1 VGNC VGNC:29393
Rattus norvegicus GLCCI1 RGD RGD:1563612
Macaca mulatta GLCCI1 VGNC VGNC:81317
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