2. Gene
  3. Adrb3 - adrenergic receptor, beta 3 Gene

Adrb3 - adrenergic receptor, beta 3 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Adrb-3; beta 3-AR

基因 ID: 11556 | 基因类型: protein coding

关于 Adrb3

功能概要

Enables beta-3 Adrenergic Receptor binding activity. Involved in positive regulation of cold-induced thermogenesis. Acts upstream of or within several processes, including brown fat cell differentiation; diet induced thermogenesis; and norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure. Located in membrane. Is expressed in central nervous system; early conceptus; oocyte; and retina. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); arthritis (multiple); dilated cardiomyopathy 1H; obesity; and type 2 diabetes mellitus. Orthologous to human ADRB3 (adrenoceptor beta 3). [provided by Alliance of Genome Resources, Apr 2022]

Adrb3 基因产物(1)

mRNA Protein Name
NM_013462.3 NP_038490.2 beta-3 adrenergic receptor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables beta-3 adrenergic receptor binding IDA
IDA: 通过直接分析推断
7738011 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within adenylate cyclase-activating G protein-coupled receptor signaling pathway IDA
IDA: 通过直接分析推断
7738011 MGI
acts upstream of or within brown fat cell differentiation IGI
IGI: 通过遗传相互作用推断
12387862 MGI
acts upstream of or within diet induced thermogenesis IGI
IGI: 通过遗传相互作用推断
12161655 MGI
acts upstream of or within heat generation IGI
IGI: 通过遗传相互作用推断
12161655 MGI
acts upstream of or within negative regulation of multicellular organism growth IGI
IGI: 通过遗传相互作用推断
12387862 MGI
acts upstream of or within norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure IDA
IDA: 通过直接分析推断
10358009 MGI
involved in positive regulation of cold-induced thermogenesis IGI
IGI: 通过遗传相互作用推断
12387862 MGI
involved in positive regulation of cold-induced thermogenesis IMP
IMP: 通过突变表型推断
7493988 MGI
acts upstream of or within response to cold IGI
IGI: 通过遗传相互作用推断
12161655 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in membrane IDA
IDA: 通过直接分析推断
7738011 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

beta-3 adrenergic receptor

Beta-3 AR

beta-3 adrenoceptor

beta-3 adrenoreceptor

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS00416 ADRB3 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS19404 Adrb3 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS25896 Adrb3 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Adrb3 NCBI NCBI:155
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