2. Gene
  3. Plod1 - procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 Gene

Plod1 - procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: Plod

基因 ID: 116552 | 基因类型: protein coding

关于 Plod1

功能概要

Enables several functions, including L-ascorbic acid binding activity; ferrous iron binding activity; and procollagen-lysine 5-dioxygenase activity. Involved in cellular response to hormone stimulus; peptidyl-lysine hydroxylation; and response to hypoxia. Predicted to be located in rough endoplasmic reticulum membrane. Predicted to be part of catalytic complex. Predicted to be active in endoplasmic reticulum. Biomarker of hypothyroidism. Human ortholog(s) of this gene implicated in Ehlers-Danlos syndrome kyphoscoliotic type 1. Orthologous to human PLOD1 (procollagen-lysine,2-oxoglutarate 5-dioxygenase 1). [provided by Alliance of Genome Resources, Apr 2022]

Plod1 基因产物(1)

mRNA Protein Name
NM_053827.2 NP_446279.2 procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 precursor
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables L-ascorbic acid binding IMP
IMP: 通过突变表型推断
11714250 RGD
enables ferrous iron binding IMP
IMP: 通过突变表型推断
11714250 RGD
enables peptide binding IDA
IDA: 通过直接分析推断
11714250 RGD
enables peptide binding IMP
IMP: 通过突变表型推断
11714250 RGD
enables procollagen-lysine 5-dioxygenase activity IDA
IDA: 通过直接分析推断
11714250 RGD
enables procollagen-lysine 5-dioxygenase activity IMP
IMP: 通过突变表型推断
11714250 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to hormone stimulus IEP
IEP: 通过表达模式推断
15817667 RGD
involved in peptidyl-lysine hydroxylation IDA
IDA: 通过直接分析推断
7578263 RGD
involved in response to hypoxia IEP
IEP: 通过表达模式推断
14622280 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

procollagen-lysine,2-oxoglutarate 5-dioxygenase 1

LH1

lysyl hydroxylase 1

procollagen-lysine 1, 2-oxoglutarate 5-dioxygenase 1

procollagen-lysine, 2-oxoglutarate 5-dioxygenase (lysine hydroxylase, Ehlers-Danlos syndrome type VI)

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS10728 PLOD1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS21027 Plod1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS27544 Plod1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Plod1 NCBI NCBI:5351
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