2. Gene
  3. Dusp6 - dual specificity phosphatase 6 Gene

Dusp6 - dual specificity phosphatase 6 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: Mkp3

基因 ID: 116663 | 基因类型: protein coding

关于 Dusp6

功能概要

Enables protein tyrosine/serine/threonine Phosphatase activity. Involved in several processes, including negative regulation of ERK1 and ERK2 cascade; positive regulation of cell death; and response to growth factor. Located in cytosol. Biomarker of brain ischemia; pancreatitis; and visual epilepsy. Human ortholog(s) of this gene implicated in hypogonadotropic hypogonadism 19 with or without anosmia. Orthologous to human DUSP6 (dual specificity Phosphatase 6). [provided by Alliance of Genome Resources, Apr 2022]

Dusp6 基因产物(1)

mRNA Protein Name
NM_053883.3 NP_446335.1 dual specificity protein phosphatase 6
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein tyrosine/serine/threonine phosphatase activity IDA
IDA: 通过直接分析推断
8631996 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cell differentiation IEP
IEP: 通过表达模式推断
8631996 RGD
involved in negative regulation of ERK1 and ERK2 cascade IDA
IDA: 通过直接分析推断
8626780 RGD
involved in response to growth factor IEP
IEP: 通过表达模式推断
9559664 RGD
involved in response to organic cyclic compound IEP
IEP: 通过表达模式推断
17881770 RGD
involved in response to xenobiotic stimulus IEP
IEP: 通过表达模式推断
11701771 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

dual specificity protein phosphatase 6

MAP kinase phosphatase 3

MKP-3

mitogen-activated protein kinase phosphatase 3

相关产品

Pre-clinical Phase
生物活性分子 (8)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-115502 BCI Inhibitor 99.73% 否
HY-115502A BCI hydrochloride Inhibitor 99.93% 否
HY-RS04067 DUSP6 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-126390 (E/Z)-BCI 99.38% 否
HY-168012 Pan-RAS-IN-6 Inhibitor / 否
HY-181889 KRAS G12C-IN-75 Inhibitor / 否
HY-RS17007 Dusp6 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23450 Dusp6 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Dusp6 NCBI NCBI:1848
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