1. Gene
  2. Zfp36l2 - zinc finger protein 36, C3H type-like 2 Gene

Zfp36l2 - zinc finger protein 36, C3H type-like 2 Gene

种属: Mus musculus

同用名: Brf2; ERF2; Tis11d

基因 ID: 12193 | 基因类型: protein coding

关于 Zfp36l2

功能概要

Enables mRNA 3'-UTR AU-rich region binding activity. Involved in several processes, including hemopoiesis; negative regulation of cell differentiation; and positive regulation of mRNA catabolic process. Acts upstream of or within hemopoiesis and nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay. Located in cytoplasm and nucleus. Is expressed in several structures, including alimentary system; brain; early conceptus; immune system; and reproductive system. Orthologous to human ZFP36L2 (ZFP36 ring finger protein like 2). [provided by Alliance of Genome Resources, Apr 2022]

Zfp36l2 基因产物(1)

mRNA Protein Name
NM_001001806.2 NP_001001806.1 mRNA decay activator protein ZFP36L2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables mRNA 3'-UTR AU-rich region binding IDA
IDA: 通过直接分析推断
20622884 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in 3'-UTR-mediated mRNA destabilization IDA
IDA: 通过直接分析推断
20622884 MGI
involved in MAPK cascade IDA
IDA: 通过直接分析推断
24733888 MGI
involved in T cell differentiation in thymus IGI
IGI: 通过遗传相互作用推断
20622884 MGI
involved in T cell differentiation in thymus IMP
IMP: 通过突变表型推断
20622884 MGI
involved in cellular response to fibroblast growth factor stimulus IDA
IDA: 通过直接分析推断
24733888 MGI
involved in definitive hemopoiesis IMP
IMP: 通过突变表型推断
19633199 MGI
acts upstream of or within hemopoiesis IMP
IMP: 通过突变表型推断
19633199 MGI
involved in hemopoiesis IMP
IMP: 通过突变表型推断
23748442 MGI
involved in mRNA catabolic process IDA
IDA: 通过直接分析推断
22367205 MGI
involved in negative regulation of fat cell differentiation IDA
IDA: 通过直接分析推断
22701344 MGI
involved in negative regulation of mitotic cell cycle phase transition IMP
IMP: 通过突变表型推断
27102483 MGI
involved in negative regulation of stem cell differentiation IMP
IMP: 通过突变表型推断
23748442 MGI
acts upstream of or within nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay IDA
IDA: 通过直接分析推断
15814898 MGI
involved in positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay IDA
IDA: 通过直接分析推断
22367205 MGI
involved in regulation of B cell differentiation IMP
IMP: 通过突变表型推断
27102483 MGI
acts upstream of or within regulation of mRNA stability IDA
IDA: 通过直接分析推断
15467755 MGI
involved in regulation of mRNA stability IDA
IDA: 通过直接分析推断
20622884 MGI
involved in somatic stem cell division IMP
IMP: 通过突变表型推断
23748442 MGI
involved in somatic stem cell population maintenance IMP
IMP: 通过突变表型推断
23748442 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
11796723 MGI
located in nucleus IDA
IDA: 通过直接分析推断
11796723 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

mRNA decay activator protein ZFP36L2

TPA-induced sequence 11d

ZFP36-like 2

butyrate response factor 2

zinc finger protein 36, C3H1 type-like 2

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Zfp36l2 NCBI NCBI:678