2. Gene
  3. Cdk5r1 - cyclin-dependent kinase 5, regulatory subunit 1 (p35) Gene

Cdk5r1 - cyclin-dependent kinase 5, regulatory subunit 1 (p35) Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: p25; p35; Cdk5r; D11Bwg0379e

基因 ID: 12569 | 基因类型: protein coding

关于 Cdk5r1

功能概要

Enables several functions, including HSP90 protein binding activity; cyclin-dependent protein serine/threonine kinase activator activity; and enzyme binding activity. Involved in several processes, including Ephrin Receptor signaling pathway; nervous system development; and regulation of Cytoskeleton organization. Acts upstream of or within several processes, including G1 to G0 transition involved in cell differentiation; nervous system development; and serine phosphorylation of STAT protein. Located in cytoplasm and nucleus. Is expressed in several structures, including alimentary system; genitourinary system; integumental system; nervous system; and sensory organ. Used to study attention deficit hyperactivity disorder. Human ortholog(s) of this gene implicated in Alzheimer's disease. Orthologous to human CDK5R1 (cyclin dependent kinase 5 regulatory subunit 1). [provided by Alliance of Genome Resources, Apr 2022]

Cdk5r1 基因产物(1)

mRNA Protein Name
NM_009871.3 NP_034001.1 cyclin-dependent kinase 5 activator 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables Hsp90 protein binding IPI
IPI: 通过物理相互作用推断
17517623 MGI
enables actin binding IPI
IPI: 通过物理相互作用推断
19118186 MGI
enables actin filament binding IPI
IPI: 通过物理相互作用推断
19118186 MGI
enables cyclin-dependent protein serine/threonine kinase activator activity IMP
IMP: 通过突变表型推断
11517264 MGI
enables ionotropic glutamate receptor binding IPI
IPI: 通过物理相互作用推断
19118186 MGI
enables protease binding IPI
IPI: 通过物理相互作用推断
19118186 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
11276227 MGI
enables protein kinase binding IPI
IPI: 通过物理相互作用推断
19118186 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within G1 to G0 transition involved in cell differentiation IMP
IMP: 通过突变表型推断
21566658 MGI
involved in axon guidance IMP
IMP: 通过突变表型推断
10545161 MGI
involved in axonal fasciculation IMP
IMP: 通过突变表型推断
10545161 MGI
involved in brain development IMP
IMP: 通过突变表型推断
10545161 MGI
acts upstream of or within cerebellum development IGI
IGI: 通过遗传相互作用推断
11517264 MGI
acts upstream of or within cerebellum development IMP
IMP: 通过突变表型推断
11226314 MGI
involved in cerebral cortex radially oriented cell migration IMP
IMP: 通过突变表型推断
20624590 MGI
involved in ephrin receptor signaling pathway IMP
IMP: 通过突变表型推断
17143272 MGI
acts upstream of or within hippocampus development IGI
IGI: 通过遗传相互作用推断
11517264 MGI
acts upstream of or within layer formation in cerebral cortex IGI
IGI: 通过遗传相互作用推断
11517264 MGI
involved in neuron cell-cell adhesion IMP
IMP: 通过突变表型推断
10753743 MGI
involved in neuron migration IDA
IDA: 通过直接分析推断
9010203 MGI
acts upstream of or within neuron migration IGI
IGI: 通过遗传相互作用推断
11226314 MGI
acts upstream of or within positive regulation of protein kinase activity IGI
IGI: 通过遗传相互作用推断
11517264 MGI
acts upstream of or within positive regulation of protein targeting to membrane IDA
IDA: 通过直接分析推断
18054859 MGI
involved in regulation of actin cytoskeleton organization IMP
IMP: 通过突变表型推断
20624590 MGI
involved in regulation of dendritic spine morphogenesis IMP
IMP: 通过突变表型推断
17143272 MGI
involved in regulation of microtubule cytoskeleton organization IMP
IMP: 通过突变表型推断
20624590 MGI
acts upstream of or within serine phosphorylation of STAT protein IDA
IDA: 通过直接分析推断
15096606 MGI
acts upstream of or within superior olivary nucleus maturation IGI
IGI: 通过遗传相互作用推断
11517264 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
15123626 MGI
located in nucleus IDA
IDA: 通过直接分析推断
15096606 MGI
part of protein kinase 5 complex IPI
IPI: 通过物理相互作用推断
18325333 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

cyclin-dependent kinase 5 activator 1

CDK5 activator 1

TPKII regulatory subunit

cyclin-dependent kinase 5 regulatory subunit 1

cyclin-dependent kinase 5, regulatory subunit (p35) 1

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS02387 CDK5R1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS20536 Cdk5r1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS27045 Cdk5r1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Cdk5r1 NCBI NCBI:8851
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