2. Gene
  3. Cfl2 - cofilin 2, muscle Gene

Cfl2 - cofilin 2, muscle Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

基因 ID: 12632 | 基因类型: protein coding

关于 Cfl2

功能概要

Enables actin filament binding activity. Involved in actin filament fragmentation and skeletal muscle tissue development. Acts upstream of or within actin filament organization; muscle cell cellular homeostasis; and sarcomere organization. Predicted to be located in Z disc. Predicted to be active in actin Cytoskeleton and cytoplasm. Is expressed in heart ventricle; limb musculature; myotome; and neural retinal epithelium. Human ortholog(s) of this gene implicated in nemaline myopathy 7. Orthologous to human CFL2 (cofilin 2). [provided by Alliance of Genome Resources, Apr 2022]

Cfl2 基因产物(1)

mRNA Protein Name
NM_007688.2 NP_031714.1 cofilin-2
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables actin filament binding IDA
IDA: 通过直接分析推断
11809832 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within actin filament depolymerization IDA
IDA: 通过直接分析推断
24840128 MGI
involved in actin filament depolymerization IDA
IDA: 通过直接分析推断
11809832 MGI
acts upstream of or within actin filament depolymerization IGI
IGI: 通过遗传相互作用推断
24840128 MGI
involved in actin filament fragmentation IDA
IDA: 通过直接分析推断
11809832 MGI
acts upstream of or within actin filament organization IMP
IMP: 通过突变表型推断
22343409 MGI
acts upstream of or within muscle cell cellular homeostasis IMP
IMP: 通过突变表型推断
22343409 MGI
acts upstream of or within sarcomere organization IMP
IMP: 通过突变表型推断
22343409 MGI
involved in skeletal muscle tissue development IMP
IMP: 通过突变表型推断
24598388 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

cofilin-2

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS02569 CFL2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS19883 Cfl2 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS26382 Cfl2 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Cfl2 NCBI NCBI:1073
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