2. Gene
  3. WTIP - WT1 interacting protein Gene

WTIP - WT1 interacting protein Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：WT1 相互作用蛋白

种属: Homo sapiens

基因 ID: 126374 | 基因类型: protein coding

关于 WTIP

Cytogenetic location: 19q13.11 Genomic coordinates (GRCh38): 19:34,481,758-34,512,304 (from NCBI)

This gene has 2 transcripts (splice variants), 196 orthologues and 2 paralogues. Broad expression in fat (RPKM 6.5), ovary (RPKM 5.4) and 23 other tissues.

功能概要

预测启用转录辅阻遏物活性。参与多个过程，包括河马信号的负调控； miRNA 对基因沉默的正调控；和对缺氧的反应。作用于 miRNA 基因沉默的上游或内部。位于 P 体。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable transcription corepressor activity. Involved in several processes, including negative regulation of hippo signaling; positive regulation of gene silencing by miRNA; and response to hypoxia. Acts upstream of or within gene silencing by miRNA. Located in P-body. [provided by Alliance of Genome Resources, Apr 2022]

WTIP 基因产物(1)

mRNA Protein Name
NM_001080436.2 NP_001073905.1 Wilms tumor protein 1-interacting protein

WTIP 蛋白结构

LIM

LIM: LIM domain (225 - 279)

LIM

LIM: LIM domain (290 - 344)

LIM

LIM: LIM domain (350 - 414)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 430 a.a.
蛋白主名 其他名称

Wilms tumor protein 1-interacting protein

Wilms tumor 1 interacting protein

关联疾病

疾病名称 别名
Wilms Tumor 1

Nephroblastoma

Wilms Tumor

WT1

Wilms' Tumor

Bilateral Wilms Tumor

Wilms Tumor, Type 1

Wilms Tumor, Somatic

Adult Nephroblastoma

Wt1 Disorder

Renal Embryonic Tumor

Adult Kidney Wilms Tumor

Childhood Kidney Wilms Tumor

Nonanaplastic Kidney Wilms Tumor
Prolidase Deficiency

Hyperimidodipeptiduria

Imidodipeptidase Deficiency

Peptidase Deficiency

PD

Deficiency Of Prolidase

Imidodipeptiduria

Proline Dipeptidase Deficiency
Chromosome 19q13.11 Deletion Syndrome

19q13.11 Microdeletion Syndrome

Monosomy 19q13.11

Del(19)(Q13.11)
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS15855 WTIP Human Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Bos taurus WTIP VGNC VGNC:52261
Rattus norvegicus WTIP RGD RGD:1306411
Mus musculus WTIP MGD MGI:2141920
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