1. Gene
  2. Coro1a - coronin, actin binding protein 1A Gene

Coro1a - coronin, actin binding protein 1A Gene

种属: Mus musculus

同用名: p57; Lmb3; TACO; Clabp

基因 ID: 12721 | 基因类型: protein coding

关于 Coro1a

功能概要

This gene encodes a member of the WD repeat coronin family. The encoded protein may bind actin and interact with microtubules. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2014]

Coro1a 基因产物(4)

mRNA Protein Name
NM_001301374.2 NP_001288303.1 coronin-1A
NM_001412247.1 NP_001399176.1 coronin-1A
NM_001412248.1 NP_001399177.1 coronin-1A
NM_009898.4 NP_034028.1 coronin-1A
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables actin filament binding IDA
IDA: 通过直接分析推断
18836449 MGI
enables cytoskeletal protein binding IMP
IMP: 通过突变表型推断
15800061 MGI
enables identical protein binding IPI
IPI: 通过物理相互作用推断
15800061 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
18836449 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of T cell activation IMP
IMP: 通过突变表型推断
18199416 MGI
acts upstream of or within T cell homeostasis IMP
IMP: 通过突变表型推断
16902139 MGI
acts upstream of T cell migration IMP
IMP: 通过突变表型推断
18199416 MGI
acts upstream of T cell proliferation IMP
IMP: 通过突变表型推断
18199416 MGI
acts upstream of or within actin filament organization IMP
IMP: 通过突变表型推断
18199416 MGI
acts upstream of or within calcium ion transport IMP
IMP: 通过突变表型推断
18199416 MGI
acts upstream of or within cellular response to interleukin-4 IDA
IDA: 通过直接分析推断
9798653 MGI
acts upstream of or within early endosome to recycling endosome transport IMP
IMP: 通过突变表型推断
24270184 MGI
acts upstream of or within epithelial cell migration IMP
IMP: 通过突变表型推断
16902139 MGI
acts upstream of or within establishment of localization in cell IMP
IMP: 通过突变表型推断
18199416 MGI
acts upstream of or within homeostasis of number of cells within a tissue IMP
IMP: 通过突变表型推断
18836449 MGI
acts upstream of or within leukocyte chemotaxis IMP
IMP: 通过突变表型推断
16902139 MGI
acts upstream of or within negative regulation of neuron apoptotic process IGI
IGI: 通过遗传相互作用推断
24270184 MGI
acts upstream of or within negative regulation of vesicle fusion IMP
IMP: 通过突变表型推断
24270184 MGI
acts upstream of or within nerve growth factor signaling pathway IGI
IGI: 通过遗传相互作用推断
24270184 MGI
acts upstream of neuron apoptotic process IGI
IGI: 通过遗传相互作用推断
24270184 MGI
acts upstream of or within positive regulation of T cell activation IMP
IMP: 通过突变表型推断
18199416 MGI
acts upstream of or within positive regulation of T cell migration IMP
IMP: 通过突变表型推断
18199416 MGI
acts upstream of or within positive regulation of T cell proliferation IMP
IMP: 通过突变表型推断
18199416 MGI
acts upstream of or within regulation of actin filament polymerization IMP
IMP: 通过突变表型推断
18836449 MGI
acts upstream of or within regulation of actin polymerization or depolymerization IMP
IMP: 通过突变表型推断
16902139 MGI
acts upstream of or within regulation of cell shape IMP
IMP: 通过突变表型推断
18836449 MGI
acts upstream of or within regulation of release of sequestered calcium ion into cytosol IGI
IGI: 通过遗传相互作用推断
24270184 MGI
acts upstream of or within response to cytokine IMP
IMP: 通过突变表型推断
18836449 MGI
acts upstream of or within thymocyte migration IMP
IMP: 通过突变表型推断
18836449 MGI
acts upstream of or within uropod organization IMP
IMP: 通过突变表型推断
16902139 MGI
acts upstream of vesicle fusion IMP
IMP: 通过突变表型推断
24270184 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in actin cytoskeleton IDA
IDA: 通过直接分析推断
15800061 MGI
located in axon IDA
IDA: 通过直接分析推断
24270184 MGI
located in cell leading edge IDA
IDA: 通过直接分析推断
18836449 MGI
located in cell-cell junction IDA
IDA: 通过直接分析推断
23793062 MGI
located in early endosome IDA
IDA: 通过直接分析推断
24270184 MGI
is active in glutamatergic synapse IDA
IDA: 通过直接分析推断
24667537 MGI
located in immunological synapse IDA
IDA: 通过直接分析推断
18199416 MGI
located in plasma membrane IDA
IDA: 通过直接分析推断
15800061 MGI
is active in stereocilium tip EXP
EXP: 通过实验结果推断
26754646 MGI
is active in synapse IDA
IDA: 通过直接分析推断
24667537 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

coronin-1A

clipin-A

coronin 1

coronin-like actin binding protein

coronin-like protein A

coronin-like protein p57

tryptophan aspartate-containing coat protein

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Coro1a NCBI NCBI:11151