2. Gene
  3. Cplx1 - complexin 1 Gene

Cplx1 - complexin 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: 921-S

基因 ID: 12889 | 基因类型: protein coding

关于 Cplx1

功能概要

Enables neurotransmitter transmembrane transporter activity. Involved in regulation of synaptic vesicle fusion to presynaptic active zone membrane and secretion by cell. Located in Schaffer collateral - CA1 synapse; glutamatergic synapse; and postsynapse. Part of SNARE complex. Is active in calyx of Held. Is expressed in nervous system; retina; and tongue. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 63. Orthologous to human CPLX1 (complexin 1). [provided by Alliance of Genome Resources, Apr 2022]

Cplx1 基因产物(1)

mRNA Protein Name
NM_007756.3 NP_031782.3 complexin-1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables lipid binding EXP
EXP: 通过实验结果推断
35777466 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in insulin secretion IMP
IMP: 通过突变表型推断
15126625 MGI
involved in regulation of exocytic insertion of neurotransmitter receptor to postsynaptic membrane IDA
IDA: 通过直接分析推断
22284181 MGI
involved in regulation of exocytic insertion of neurotransmitter receptor to postsynaptic membrane IMP
IMP: 通过突变表型推断
22284181 MGI
involved in regulation of synaptic vesicle fusion to presynaptic active zone membrane IDA
IDA: 通过直接分析推断
11163241 MGI
involved in regulation of synaptic vesicle fusion to presynaptic active zone membrane IMP
IMP: 通过突变表型推断
11163241 MGI
involved in synaptic vesicle exocytosis IMP
IMP: 通过突变表型推断
15126625 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of SNARE complex IDA
IDA: 通过直接分析推断
15126625 MGI
is active in Schaffer collateral - CA1 synapse IDA
IDA: 通过直接分析推断
22284181 MGI
is active in Schaffer collateral - CA1 synapse IMP
IMP: 通过突变表型推断
22284181 MGI
is active in calyx of Held IDA
IDA: 通过直接分析推断
26019341 MGI
is active in glutamatergic synapse IDA
IDA: 通过直接分析推断
11163241 MGI
is active in glutamatergic synapse IMP
IMP: 通过突变表型推断
11163241 MGI
is active in postsynapse IDA
IDA: 通过直接分析推断
26019341 MGI
is active in presynapse IDA
IDA: 通过直接分析推断
26019341 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

complexin-1

CPX I

complexin I

synaphin-2

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS03097 CPLX1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS22455 Cplx1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS28978 Cplx1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Cplx1 NCBI NCBI:10815
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