2. Gene
  3. Cradd - CASP2 and RIPK1 domain containing adaptor with death domain Gene

Cradd - CASP2 and RIPK1 domain containing adaptor with death domain Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: RAIDD

基因 ID: 12905 | 基因类型: protein coding

关于 Cradd

功能概要

Predicted to enable death domain binding activity; protease binding activity; and protein-macromolecule adaptor activity. Acts upstream of or within activation of cysteine-type endopeptidase activity involved in apoptotic process and positive regulation of apoptotic signaling pathway. Located in cytoplasm and nucleus. Is expressed in several structures, including branchial arch; central nervous system; genitourinary system; heart; and sensory organ. Human ortholog(s) of this gene implicated in autosomal recessive non-syndromic intellectual disability. Orthologous to human CRADD (CASP2 and RIPK1 domain containing adaptor with death domain). [provided by Alliance of Genome Resources, Apr 2022]

Cradd 基因产物(8)

mRNA Protein Name
NM_001330138.1 NP_001317067.1 death domain-containing protein CRADD
NM_001330141.1 NP_001317070.1 death domain-containing protein CRADD
NM_001330175.1 NP_001317104.1 death domain-containing protein CRADD
NM_009950.3 NP_034080.1 death domain-containing protein CRADD
NM_001330138.1 NP_001317067.1 death domain-containing protein CRADD
NM_001330141.1 NP_001317070.1 death domain-containing protein CRADD
NM_001330175.1 NP_001317104.1 death domain-containing protein CRADD
NM_009950.3 NP_034080.1 death domain-containing protein CRADD
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within activation of cysteine-type endopeptidase activity involved in apoptotic process IGI
IGI: 通过遗传相互作用推断
16183742 MGI
acts upstream of or within positive regulation of apoptotic signaling pathway IGI
IGI: 通过遗传相互作用推断
16183742 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
22279524 MGI
located in nucleus IDA
IDA: 通过直接分析推断
22279524 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

death domain-containing protein CRADD

RIP-associated protein with a death domain

caspase and RIP adapter with death domain

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS03138 CRADD Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS20004 Cradd Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS26507 Cradd Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Cradd NCBI NCBI:8738
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