1. Gene
  2. Dffa - DNA fragmentation factor, alpha subunit Gene

Dffa - DNA fragmentation factor, alpha subunit Gene

种属: Mus musculus

同用名: ICAD; DFF35; Dff45; ICAD-L; ICAD-S; A330085O09Rik

基因 ID: 13347 | 基因类型: protein coding

关于 Dffa

功能概要

Predicted to enable deoxyribonuclease inhibitor activity; protein domain specific binding activity; and protein folding chaperone. Acts upstream of or within negative regulation of apoptotic DNA fragmentation; positive regulation of apoptotic process; and thymocyte apoptotic process. Predicted to be located in several cellular components, including chromatin; cytosol; and nucleus. Predicted to be part of protein-containing complex. Is expressed in several structures, including brain; heart; hemolymphoid system gland; liver; and metanephros. Orthologous to human DFFA (DNA fragmentation factor subunit alpha). [provided by Alliance of Genome Resources, Apr 2022]

Dffa 基因产物(2)

mRNA Protein Name
NM_001025296.2 NP_001020467.1 DNA fragmentation factor subunit alpha isoform a
NM_010044.3 NP_034174.2 DNA fragmentation factor subunit alpha isoform b
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
14557248 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within negative regulation of apoptotic DNA fragmentation IMP
IMP: 通过突变表型推断
10601318 MGI
acts upstream of or within positive regulation of apoptotic process IMP
IMP: 通过突变表型推断
14663139 MGI
acts upstream of or within thymocyte apoptotic process IMP
IMP: 通过突变表型推断
10601318 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

DNA fragmentation factor subunit alpha

DNA fragmentation factor 45 kDa subunit

inhibitor of CAD

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Dffa NCBI NCBI:1676