1. Gene
  2. Dlx1 - distal-less homeobox 1 Gene

Dlx1 - distal-less homeobox 1 Gene

种属: Mus musculus

同用名: Dlx; Dlx-1

基因 ID: 13390 | 基因类型: protein coding

关于 Dlx1

功能概要

The protein encoded by this gene is a homeobox-containing transcription factor involved in development. The encoded protein plays a role in craniofacial patterning, as well as in bone, placenta, and sensory organ formation. [provided by RefSeq, Aug 2015]

Dlx1 基因产物(1)

mRNA Protein Name
NM_010053.2 NP_034183.1 homeobox protein DLX-1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables DNA binding IDA
IDA: 通过直接分析推断
9415433 MGI
enables DNA-binding transcription factor activity, RNA polymerase II-specific IDA
IDA: 通过直接分析推断
22920256 MGI
enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IDA
IDA: 通过直接分析推断
14769946 MGI
enables chromatin binding IDA
IDA: 通过直接分析推断
14769946 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
21875655 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within GABAergic neuron differentiation IGI
IGI: 通过遗传相互作用推断
11163262 MGI
acts upstream of Notch signaling pathway IGI
IGI: 通过遗传相互作用推断
23042297 MGI
acts upstream of or within cerebral cortex GABAergic interneuron differentiation IGI
IGI: 通过遗传相互作用推断
15028753 MGI
acts upstream of or within cerebral cortex GABAergic interneuron fate commitment IGI
IGI: 通过遗传相互作用推断
17678855 MGI
acts upstream of or within embryonic skeletal system development IGI
IGI: 通过遗传相互作用推断
9187081 MGI
acts upstream of or within embryonic skeletal system development IMP
IMP: 通过突变表型推断
9187081 MGI
acts upstream of or within forebrain neuron differentiation IGI
IGI: 通过遗传相互作用推断
11163262 MGI
acts upstream of or within hippocampus development IGI
IGI: 通过遗传相互作用推断
11163262 MGI
acts upstream of or within negative regulation of Notch signaling pathway IGI
IGI: 通过遗传相互作用推断
23042297 MGI
acts upstream of or within negative regulation of neuron apoptotic process IMP
IMP: 通过突变表型推断
16007083 MGI
acts upstream of or within negative regulation of oligodendrocyte differentiation IGI
IGI: 通过遗传相互作用推断
17678855 MGI
involved in negative regulation of photoreceptor cell differentiation IMP
IMP: 通过突变表型推断
21875655 MGI
acts upstream of or within negative regulation of transcription by RNA polymerase II IGI
IGI: 通过遗传相互作用推断
17678855 MGI
acts upstream of or within neuroblast differentiation IMP
IMP: 通过突变表型推断
12397111 MGI
acts upstream of neuron apoptotic process IMP
IMP: 通过突变表型推断
16007083 MGI
acts upstream of or within odontogenesis of dentin-containing tooth IGI
IGI: 通过遗传相互作用推断
9187081 MGI
acts upstream of oligodendrocyte differentiation IGI
IGI: 通过遗传相互作用推断
17678855 MGI
involved in positive regulation of amacrine cell differentiation IMP
IMP: 通过突变表型推断
21875655 MGI
involved in positive regulation of cell differentiation IMP
IMP: 通过突变表型推断
21875655 MGI
involved in positive regulation of transcription by RNA polymerase II IMP
IMP: 通过突变表型推断
21875655 MGI
acts upstream of or within proximal/distal pattern formation IGI
IGI: 通过遗传相互作用推断
9187081 MGI
acts upstream of or within proximal/distal pattern formation IMP
IMP: 通过突变表型推断
9187081 MGI
involved in regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
22920256 MGI
acts upstream of or within regulation of transcription by RNA polymerase II IGI
IGI: 通过遗传相互作用推断
17678855 MGI
acts upstream of or within subpallium development IGI
IGI: 通过遗传相互作用推断
23042297 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in nucleus IDA
IDA: 通过直接分析推断
10516593 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

homeobox protein DLX-1

DII B

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Dlx1 NCBI NCBI:1745