Dnm2 - dynamin 2 Gene

种属: Mus musculus

同用名: Dyn2; Udnm; b2b2159Clo

关于 Dnm2

功能概要

Predicted to enable several functions, including D2 Dopamine Receptor binding activity; enzyme binding activity; and protein domain specific binding activity. Involved in synaptic vesicle endocytosis. Acts upstream of or within aorta development; coronary vasculature development; and ventricular septum development. Located in clathrin-coated pit and photoreceptor inner segment. Is expressed in several structures, including alimentary system; central nervous system; sensory organ; skin; and white fat. Used to study centronuclear myopathy; cystic kidney disease; and myopathy. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease dominant intermediate B; centronuclear myopathy 1; and lethal congenital contracture syndrome. Orthologous to human DNM2 (Dynamin 2). [provided by Alliance of Genome Resources, Apr 2022]