Dpm1 - dolichol-phosphate (beta-D) mannosyltransferase 1 Gene

种属: Mus musculus

关于 Dpm1

功能概要

Enables dolichyl-phosphate beta-D-mannosyltransferase activity. Acts upstream of or within GPI anchor biosynthetic process and dolichol metabolic process. Predicted to be located in endoplasmic reticulum and membrane. Predicted to be part of dolichol-phosphate-mannose synthase complex. Predicted to be active in endoplasmic reticulum membrane. Is expressed in several structures, including alimentary system; genitourinary system; integumental system; nervous system; and sensory organ. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation Ie. Orthologous to human DPM1 (dolichyl-phosphate mannosyltransferase subunit 1, catalytic). [provided by Alliance of Genome Resources, Apr 2022]