2. Gene
  3. Eif2s1 - eukaryotic translation initiation factor 2, subunit 1 alpha Gene

Eif2s1 - eukaryotic translation initiation factor 2, subunit 1 alpha Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: 35kDa; Eif2a; eIF2alpha; 0910001O23Rik; 2410026C18Rik

基因 ID: 13665 | 基因类型: protein coding

关于 Eif2s1

功能概要

Predicted to enable ribosome binding activity and translation initiation factor activity. Involved in several processes, including cellular response to amino acid starvation; negative regulation of translational initiation in response to stress; and stress granule assembly. Acts upstream of or within protein autophosphorylation; regulation of translational initiation in response to stress; and translation. Located in cytoplasmic stress granule and nucleus. Is active in synapse. Is expressed in several structures, including brain ventricular layer; jaw; nose; orbito-sphenoid; and thymus primordium. Human ortholog(s) of this gene implicated in Alzheimer's disease. Orthologous to human EIF2S1 (eukaryotic translation initiation factor 2 subunit alpha). [provided by Alliance of Genome Resources, Apr 2022]

Eif2s1 基因产物(1)

mRNA Protein Name
NM_026114.3 NP_080390.1 eukaryotic translation initiation factor 2 subunit 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
15544353 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to UV IDA
IDA: 通过直接分析推断
12176355 MGI
involved in cellular response to amino acid starvation IDA
IDA: 通过直接分析推断
11106749 MGI
involved in cellular response to oxidative stress IMP
IMP: 通过突变表型推断
27430620 MGI
involved in negative regulation of translational initiation in response to stress IDA
IDA: 通过直接分析推断
12176355 MGI
acts upstream of or within protein autophosphorylation IDA
IDA: 通过直接分析推断
19139267 MGI
acts upstream of or within regulation of translational initiation in response to stress IDA
IDA: 通过直接分析推断
15937339 MGI
involved in response to endoplasmic reticulum stress IDA
IDA: 通过直接分析推断
11106749 MGI
involved in stress granule assembly IMP
IMP: 通过突变表型推断
27430620 MGI
acts upstream of or within translation IDA
IDA: 通过直接分析推断
10882126 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
12388085 MGI
located in cytoplasmic stress granule IDA
IDA: 通过直接分析推断
19861488 MGI
located in nucleus IDA
IDA: 通过直接分析推断
12388085 MGI
is active in synapse EXP
EXP: 通过实验结果推断
16452087 MGI
is active in synapse IDA
IDA: 通过直接分析推断
16452087 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

eukaryotic translation initiation factor 2 subunit 1

eIF-2-alpha

eIF-2A

eIF-2alpha

eukaryotic translation initiation factor 2 subunit alpha

eukaryotic translation initiation factor 2A

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS04254 EIF2S1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS21851 Eif2s1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS28368 Eif2s1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Eif2s1 NCBI NCBI:1965
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