2. Gene
  3. Eif4ebp1 - eukaryotic translation initiation factor 4E binding protein 1 Gene

Eif4ebp1 - eukaryotic translation initiation factor 4E binding protein 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: 4e-bp1; PHAS-I

基因 ID: 13685 | 基因类型: protein coding

关于 Eif4ebp1

功能概要

Enables eukaryotic initiation factor 4E binding activity. Involved in IRES-dependent translational initiation of linear mRNA. Acts upstream of or within cellular response to dexamethasone stimulus; Insulin Receptor signaling pathway; and negative regulation of translational initiation. Predicted to be located in cytosol and nucleus. Predicted to be part of protein-containing complex. Predicted to be active in cytoplasm. Is expressed in several structures, including central nervous system; oocyte; pancreas tip epithelium; retina; and skeletal musculature. Human ortholog(s) of this gene implicated in lung non-small cell carcinoma. Orthologous to human EIF4EBP1 (eukaryotic translation initiation factor 4E binding protein 1). [provided by Alliance of Genome Resources, Apr 2022]

Eif4ebp1 基因产物(1)

mRNA Protein Name
NM_007918.3 NP_031944.3 eukaryotic translation initiation factor 4E-binding protein 1
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables eukaryotic initiation factor 4E binding IPI
IPI: 通过物理相互作用推断
16142217 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
7629182 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in IRES-dependent translational initiation of linear mRNA IDA
IDA: 通过直接分析推断
24553947 MGI
acts upstream of or within cellular response to dexamethasone stimulus IDA
IDA: 通过直接分析推断
17556672 MGI
acts upstream of or within insulin receptor signaling pathway IDA
IDA: 通过直接分析推断
7629182 MGI
acts upstream of or within negative regulation of translational initiation IDA
IDA: 通过直接分析推断
16142217 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

eukaryotic translation initiation factor 4E-binding protein 1

eIF4E-binding protein 1

phosphorylated heat- and acid-stable protein regulated by insulin 1

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS04277 EIF4EBP1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS20227 Eif4ebp1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS26734 Eif4ebp1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Eif4ebp1 NCBI NCBI:1978
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