2. Gene
  3. PASD1 - PAS domain containing repressor 1 Gene

PASD1 - PAS domain containing repressor 1 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：含 PAS 结构域的抑制子 1

种属: Homo sapiens

同用名: CT63; CT64; OXTES1

基因 ID: 139135 | 基因类型: protein coding

关于 PASD1

Cytogenetic location: Xq28 Genomic coordinates (GRCh38): X:151,563,675-151,676,739 (from NCBI)

This gene has 2 transcripts (splice variants), 157 orthologues and 6 paralogues. Restricted expression toward testis (RPKM 11.6).

功能概要

该基因编码一种被认为起转录因子作用的蛋白质。该蛋白是一种癌症相关抗原，可以刺激自体 T 细胞反应，因此被认为是治疗各种造血系统恶性肿瘤 (包括弥漫性大 B 细胞淋巴瘤) 的潜在免疫治疗靶点。[RefSeq 提供，2010 年 5 月]

This gene encodes a protein that is thought to function as a transcription factor. The protein is a cancer-associated antigen that can stimulate autologous T-cell responses, and it is therefore considered to be a potential immunotherapeutic target for the treatment of various hematopoietic malignancies, including diffuse large B-cell lymphoma. [provided by RefSeq, May 2010]

PASD1 基因产物(1)

mRNA Protein Name
NM_173493.3 NP_775764.2 circadian clock protein PASD1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables DNA-binding transcription factor binding IPI
IPI: 通过物理相互作用推断
25936801 GOA
enables transcription regulator inhibitor activity IDA
IDA: 通过直接分析推断
25936801 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in negative regulation of DNA-templated transcription IDA
IDA: 通过直接分析推断
25936801 GOA
involved in negative regulation of circadian rhythm IDA
IDA: 通过直接分析推断
25936801 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of Cry-Per complex IDA
IDA: 通过直接分析推断
25936801 GOA
located in nucleus IDA
IDA: 通过直接分析推断
25936801 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

circadian clock protein PASD1

PAS domain containing 1

关联疾病

疾病名称 别名
B-Cell Lymphoma

Lymphoma, B-Cell

B-Cell Lymphomas

B-Cell Lymphocytic Neoplasm

Lymphoma B-Cell

B-Cell Lymphoma Nos
Diffuse Large B-Cell Lymphoma

Dlbcl

Diffuse Large B-Cell Lymphoma, Not Otherwise Specified

Large B-Cell Diffuse Lymphoma

Lymphoma, Large B-Cell, Diffuse

Dlbcl - [Diffuse Large B-Cell Lymphoma]

Diffuse Large Beta Cell Lymphoma
Lymphoma

Lymphoid Cancer

Lymphomas

Lymphoid Cancers

Lymphoid Neoplasm

Lymphoma Nos

Nhl - [Non-Hodgkin Lymphoma]

Non-Hodgkin Lymphoma

Non-Hodgkin Lymphoma, Nos

Non-Hodgkin Malignant Lymphoma Nos
Adult Oligodendroglioma

Adult Brain Oligodendroglioma

Grade Ii Adult Oligodendroglial Tumor

Oligodendroglioma, Adult
Pilocytic Astrocytoma Of Cerebellum

Cerebellar Pilocytic Astrocytoma
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS10077 PASD1 Human Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Canis familiaris PASD1 VGNC VGNC:44269
Mus musculus PASD1 MGD MGI:2685987
Macaca mulatta PASD1 VGNC VGNC:75659
Rattus norvegicus PASD1 RGD RGD:7496877
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