1. Gene
  2. ASB5 - ankyrin repeat and SOCS box containing 5 Gene

ASB5 - ankyrin repeat and SOCS box containing 5 Gene

中文名称:含锚蛋白重复和 SOCS 框 5

种属: Homo sapiens

同用名: ASB-5

基因 ID: 140458 | 基因类型: protein coding

关于 ASB5

Cytogenetic location: 4q34.2 Genomic coordinates (GRCh38): 4:176,213,673-176,277,524 (from NCBI)

This gene has 6 transcripts (splice variants), 136 orthologues and 2 paralogues. Biased expression in prostate (RPKM 5.3), urinary bladder (RPKM 4.0) and 6 other tissues.

功能概要

由该基因编码的蛋白质是锚蛋白重复序列和含有 SOCS 盒 (ASB) 的蛋白质家族的成员。它们包含锚蛋白重复序列和 SOCS 框域。 SOCS 盒用于将细胞因子信号转导抑制因子 (SOCS) 蛋白及其结合伙伴与 elongin B 和 C 复合物偶联,可能靶向它们进行降解。已经描述了该基因的多个选择性剪接转录物变体,但它们的全长序列尚不清楚。[RefSeq 提供,2008 年 7 月]

The protein encoded by this gene is a member of the ankyrin repeat and SOCS box-containing (ASB) family of proteins. They contain ankyrin repeat sequence and SOCS box domain. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. Multiple alternatively spliced transcript variants have been described for this gene but their full length sequences are not known. [provided by RefSeq, Jul 2008]

ASB5 基因产物(2)

mRNA Protein Name
NM_001410863.1 NP_001397792.1 ankyrin repeat and SOCS box protein 5 isoform 2
NM_080874.4 NP_543150.1 ankyrin repeat and SOCS box protein 5 isoform 1

ASB5 蛋白结构

Ank_2

Ank_2: Ankyrin repeats (3 copies) (74 - 164)

Ank_2

Ank_2: Ankyrin repeats (3 copies) (173 - 263)

SOCS_box

SOCS_box: SOCS box (290 - 329)

  • 0
  • 100
  • 200
  • 300
  • 329 a.a.
蛋白主名 其他名称

ankyrin repeat and SOCS box protein 5

SOCS box protein ASB-5

ASB5 抗体

目录号 产品名 应用 反应物种
HY-P89722 ASB-5 Antibody (YA9066) WB, ICC/IF, IF-Tissue, IP, ELISA human

直系同源

种属 基因名 来源 基因 ID
Felis catus ASB5 VGNC VGNC:59961
Rattus norvegicus ASB5 RGD RGD:1565973
Canis familiaris ASB5 VGNC VGNC:38165
Bos taurus ASB5 VGNC VGNC:26198
Mus musculus ASB5 MGD MGI:1923544
Macaca mulatta ASB5 VGNC VGNC:69849