Fxr1 - FMR1 autosomal homolog 1 Gene

种属: Mus musculus

同用名: Fxr1h; Fxr1p; 1110050J02Rik; 9530073J07Rik

基因 ID: 14359 | 基因类型: protein coding

关于 Fxr1

功能概要

Enables G-quadruplex RNA binding activity and mRNA 3'-UTR binding activity. Involved in skeletal muscle organ development. Acts upstream of or within muscle organ development and negative regulation of translation. Located in several cellular components, including costamere; dendritic spine; and glutamatergic synapse. Part of polysome. Is expressed in several structures, including central nervous system; gut; musculature; sensory organ; and urinary system. Orthologous to human FXR1 (FMR1 autosomal homolog 1). [provided by Alliance of Genome Resources, Apr 2022]

Fxr1 基因产物(3)

mRNA	Protein	Name
NM_001113188.1	NP_001106659.1	RNA-binding protein FXR1 isoform 1
NM_001113189.1	NP_001106660.1	RNA-binding protein FXR1 isoform 2
NM_008053.2	NP_032079.1	RNA-binding protein FXR1 isoform 3

基因本体论

分子功能
生物过程
细胞组分

分子功能 GO 注释	逻辑证据	参考文献	来源
enables mRNA 3'-UTR AU-rich region binding	IDA IDA: 通过直接分析推断	15548538	MGI
enables mRNA binding	IDA IDA: 通过直接分析推断	28204491	MGI
enables molecular condensate scaffold activity	IDA IDA: 通过直接分析推断	32328638	MGI
enables protein binding	IPI IPI: 通过物理相互作用推断	10567518	MGI
enables ribonucleoprotein complex binding	IDA IDA: 通过直接分析推断	11178106	MGI

生物过程 GO 注释	逻辑证据	参考文献	来源
involved in dentate gyrus development	IMP IMP: 通过突变表型推断	28204491	MGI
involved in muscle organ development	IDA IDA: 通过直接分析推断	32328638	MGI
acts upstream of or within muscle organ development	IMP IMP: 通过突变表型推断	15128702	MGI
involved in muscle organ development	IMP IMP: 通过突变表型推断	30770808	MGI
involved in negative regulation of long-term synaptic potentiation	IMP IMP: 通过突变表型推断	25456134	MGI
involved in negative regulation of translation	IDA IDA: 通过直接分析推断	25456134	MGI
involved in negative regulation of tumor necrosis factor production	IDA IDA: 通过直接分析推断	15548538	MGI
involved in non-membrane-bounded organelle assembly	IDA IDA: 通过直接分析推断	35951695	MGI
involved in positive regulation of translation	IDA IDA: 通过直接分析推断	35951695	MGI
involved in post-transcriptional regulation of gene expression	IDA IDA: 通过直接分析推断	15548538	MGI
involved in post-transcriptional regulation of gene expression	IMP IMP: 通过突变表型推断	32893934	MGI
involved in regulation of circadian sleep/wake cycle, sleep	IMP IMP: 通过突变表型推断	32893934	MGI
involved in regulation of neurogenesis	IDA IDA: 通过直接分析推断	28204491	MGI
involved in regulation of synaptic transmission, glutamatergic	IMP IMP: 通过突变表型推断	25456134	MGI
involved in skeletal muscle organ development	IDA IDA: 通过直接分析推断	30770808	MGI
involved in spermatid development	IDA IDA: 通过直接分析推断	35951695	MGI

细胞组分 GO 注释	逻辑证据	参考文献	来源
located in axon	IDA IDA: 通过直接分析推断	22022532	MGI
located in costamere	IDA IDA: 通过直接分析推断	15128702	MGI
is active in cytoplasm	IDA IDA: 通过直接分析推断	35951695	MGI
located in cytosol	IDA IDA: 通过直接分析推断	30770808	MGI
located in dendrite	IDA IDA: 通过直接分析推断	22022532	MGI
located in dendritic spine	IDA IDA: 通过直接分析推断	22022532	MGI
is active in glutamatergic synapse	IDA IDA: 通过直接分析推断	27770568	MGI
is active in intracellular non-membrane-bounded organelle	IDA IDA: 通过直接分析推断	35951695	MGI
located in nucleus	IDA IDA: 通过直接分析推断	11178106	MGI
located in perinuclear region of cytoplasm	IDA IDA: 通过直接分析推断	22022532	MGI
is active in postsynapse	IDA IDA: 通过直接分析推断	27770568	MGI
located in ribonucleoprotein granule	IDA IDA: 通过直接分析推断	22022532	MGI
located in ribosome	IDA IDA: 通过直接分析推断	22022532	MGI

EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

蛋白主名

其他名称

RNA-binding protein FXR1

fragile X mental retardation syndrome-related protein 1

目录号	产品名	作用方式	纯度	Phase
HY-14908	Vidofludimus		99.14%	Phase 2

Cat. No.	产品名	作用方式	纯度	是否罕见病
HY-14908A	Vidofludimus hemicalcium		/	否
HY-RS05163	FXR1 Human Pre-designed siRNA Set A	Pre-designed Set	/	否
HY-RS20736	Fxr1 Mouse Pre-designed siRNA Set A	Pre-designed Set	/	否
HY-RS27248	Fxr1 Rat Pre-designed siRNA Set A	Pre-designed Set	/	否

直系同源

种属	基因名	来源	基因 ID
Homo sapiens	Fxr1	NCBI	NCBI:8087

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MedChemExpress (MCE) 只为有资质的科研机构、医药企业基于科学研究或药证申报的用途提供医药研发服务，不为任何个人或者非科研性质的、非用于药证申报使用等其他用途提供服务。

站点地图隐私声明

粤ICP备2021105330号-3

上海工商

沪公网安备31011502019417

沪(浦)应急管危经许[2021]201709(QFYS)

营业执照（三证合一）

Fxr1 - FMR1 autosomal homolog 1 Gene

关于 Fxr1

功能概要

Fxr1 基因产物(3)

直系同源

热门区域

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Fxr1 - FMR1 autosomal homolog 1 Gene

关于 Fxr1

功能概要

Fxr1 基因产物(3)

相关产品

直系同源

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z