2. Gene
  3. COPS9 - COP9 signalosome subunit 9 Gene

COPS9 - COP9 signalosome subunit 9 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：COP9 信号体亚基 9

种属: Homo sapiens

同用名: CSNAP; MYEOV2

基因 ID: 150678 | 基因类型: protein coding

关于 COPS9

Cytogenetic location: 2q37.3 Genomic coordinates (GRCh38): 2:240,126,548-240,136,347 (from NCBI)

This gene has 5 transcripts (splice variants) and 186 orthologues. Ubiquitous expression in brain (RPKM 12.9), fat (RPKM 12.7) and 25 other tissues.

功能概要

参与多个过程，包括细胞对紫外线的反应；蛋白质的细胞质螯合；和蛋白质 neddylation 的负调节。位于染色质；细胞质；和核质。与 COP9 信号体共定位。 [由基因组资源联盟提供，2022 年 4 月]

Involved in several processes, including cellular response to UV; cytoplasmic sequestering of protein; and negative regulation of protein neddylation. Located in chromatin; cytoplasm; and nucleoplasm. Colocalizes with COP9 signalosome. [provided by Alliance of Genome Resources, Apr 2022]

COPS9 基因产物(2)

mRNA Protein Name
NM_001163424.2 NP_001156896.1 COP9 signalosome complex subunit 9 isoform 2
NM_138336.1 NP_612209.1 COP9 signalosome complex subunit 9 isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
23776465 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to UV IDA
IDA: 通过直接分析推断
26456823 GOA
involved in cytoplasmic sequestering of protein IMP
IMP: 通过突变表型推断
23776465 GOA
involved in negative regulation of protein neddylation IMP
IMP: 通过突变表型推断
23776465 GOA
involved in positive regulation of cell population proliferation IMP
IMP: 通过突变表型推断
26456823 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of COP9 signalosome IDA
IDA: 通过直接分析推断
23776465 GOA
located in chromatin IDA
IDA: 通过直接分析推断
26456823 GOA
located in cytoplasm IDA
IDA: 通过直接分析推断
26456823 GOA
located in nucleoplasm IDA
IDA: 通过直接分析推断
23776465 GOA
located in nucleus IDA
IDA: 通过直接分析推断
26456823 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

COPS9 蛋白结构

MYEOV2

MYEOV2: Myeloma-overexpressed-like (1 - 56)

  • 0
  • 57 a.a.
蛋白主名 其他名称

COP9 signalosome complex subunit 9

CSN acidic protein

关联疾病

疾病名称 别名
Photoparoxysmal Response 1

Photosensitivity Disease

Photodermatitis

Photosensitivity Disorders

PPR1

Ppr

Photosensitivity

Photoconvulsive Reaction

Epilepsy, Photogenic

Photosensitivity Of Skin

Dermatitis, Phototoxic
Balo Concentric Sclerosis

Balo'S Concentric Sclerosis

Balo Disease

Diffuse Cerebral Sclerosis Of Schilder

Tumefactive Multiple Sclerosis

Concentric Demyelination

Balo'S Disease

Baló Concentric Sclerosis

Encephalitis Periaxialis Concentrica

Marburg Variant
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS03033 COPS9 Human Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus COPS9 RGD RGD:1596701
Mus musculus COPS9 MGD MGI:1914165
Bos taurus COPS9 VGNC VGNC:54910
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