2. Gene
  3. Hk2 - hexokinase 2 Gene

Hk2 - hexokinase 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: HKII

基因 ID: 15277 | 基因类型: protein coding

关于 Hk2

功能概要

Enables Hexokinase activity. Involved in negative regulation of mitochondrial membrane permeability and negative regulation of Reactive Oxygen Species metabolic process. Acts upstream of or within several processes, including carbohydrate phosphorylation; cellular response to leukemia inhibitory factor; and regulation of glucose import. Located in mitochondrion. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in obesity and type 2 diabetes mellitus. Orthologous to human HK2 (Hexokinase 2). [provided by Alliance of Genome Resources, Apr 2022]

Hk2 基因产物(1)

mRNA Protein Name
NM_013820.4 NP_038848.1 hexokinase-2
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables hexokinase activity IDA
IDA: 通过直接分析推断
18165236 MGI
enables hexokinase activity IMP
IMP: 通过突变表型推断
10428828 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within apoptotic mitochondrial changes IGI
IGI: 通过遗传相互作用推断
18350175 MGI
acts upstream of or within carbohydrate phosphorylation IMP
IMP: 通过突变表型推断
10428828 MGI
acts upstream of or within cellular response to leukemia inhibitory factor IEP
IEP: 通过表达模式推断
20439489 MGI
acts upstream of or within glucose metabolic process IMP
IMP: 通过突变表型推断
10428828 MGI
involved in negative regulation of mitochondrial membrane permeability IMP
IMP: 通过突变表型推断
22517678 MGI
involved in negative regulation of reactive oxygen species metabolic process IMP
IMP: 通过突变表型推断
22517678 MGI
acts upstream of or within regulation of D-glucose import IMP
IMP: 通过突变表型推断
17639019 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

hexokinase-2

HK II

hexokinase type II

相关产品

Clinical Phase
生物活性分子 (1)
目录号 产品名 作用方式
纯度 Phase
HY-101563 GSK3326595 Inhibitor 99.83% Phase 2
Pre-clinical Phase
生物活性分子 (27)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-112780 UC2288 99.82% 否
HY-155008 PROTAC HK2 Degrader-1 Degrader 98.98% 否
HY-N1990 Gypenoside XLIX 99.88% 否
HY-N7675 Flavanomarein Inhibitor 99.92% 否
HY-N0911 Rehmannioside A 99.96% 否
HY-N2445 Flavokawain C 99.79% 否
HY-N8407 Carminic acid 95.19% 否
HY-125938 Cycloartenyl ferulate 99.15% 否
HY-175035 HK-2-IN-1 Inhibitor 99.88% 否
HY-130437 p-nitro-Pifithrin-α 97.0% 否
HY-156277 SP4f Activator 99.77% 否
HY-151432 URAT1 inhibitor 3 Inhibitor 98.02% 否
HY-156276 SP4e Activator 99.72% 否
HY-156368 RIPK3-IN-4 Inhibitor / 否
HY-168717 HK-2-IN-2 Inhibitor / 否
HY-179378 XRF-1021 Inhibitor / 否
HY-180805 HK2-IN-3 / 否
HY-181652 PPARδ agonist 13 Agonist / 否
HY-182243 HK2-IN-4 / 否
HY-RS06193 HK2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS06288 HOOK2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS07101 KCNA5 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS07282 KIF2A Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS07380 KLK2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-111331 Germicidin B Inhibitor / 否
HY-RS16576 Hk2 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23009 Hk2 Rat Pre-designed siRNA Set A Pre-designed Set / 否
抗体抑制剂 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-P991808 Anti-Mouse CD90 Antibody (HK2.1) Inhibitor / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Hk2 NCBI NCBI:3099
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