2. Gene
  3. Hnrnpk - heterogeneous nuclear ribonucleoprotein K Gene

Hnrnpk - heterogeneous nuclear ribonucleoprotein K Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: KBBP; NOVA; Hnrpk

基因 ID: 15387 | 基因类型: protein coding

关于 Hnrnpk

功能概要

The protein encoded by this gene is a component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complex, and is a poly-cytosine binding protein (PCBP). It is found in multiple subcellular compartments including the nucleus, cytoplasm and mitochondria. This gene product is thought to interact with RNA, DNA, and protein, and is involved in multiple cellular processes, including transcription, chromatin remodeling, DNA damage response, signal transduction, mRNA splicing, export, and translation. Multiple transcript variants and protein isoforms exist, with some isoforms containing a unique C-terminus. There are four pseudogenes of this gene, found on chromosomes 2, 3, 7 and 13. [provided by RefSeq, Aug 2014]

Hnrnpk 基因产物(22)

mRNA Protein Name
NM_001301340.1 NP_001288269.1 heterogeneous nuclear ribonucleoprotein K isoform 1
NM_001301341.1 NP_001288270.1 heterogeneous nuclear ribonucleoprotein K isoform 1
NM_001301343.1 NP_001288272.1 heterogeneous nuclear ribonucleoprotein K isoform 1
NM_001301344.1 NP_001288273.1 heterogeneous nuclear ribonucleoprotein K isoform 3
NM_001301345.1 NP_001288274.1 heterogeneous nuclear ribonucleoprotein K isoform 4
NM_001360490.1 NP_001347419.1 heterogeneous nuclear ribonucleoprotein K isoform 2
NM_001360491.1 NP_001347420.1 heterogeneous nuclear ribonucleoprotein K isoform 5
NM_001360493.1 NP_001347422.1 heterogeneous nuclear ribonucleoprotein K isoform 6
NM_001360494.1 NP_001347423.1 heterogeneous nuclear ribonucleoprotein K isoform 3
NM_001360495.1 NP_001347424.1 heterogeneous nuclear ribonucleoprotein K isoform 4
NM_025279.3 NP_079555.1 heterogeneous nuclear ribonucleoprotein K isoform 2
NM_001301340.1 NP_001288269.1 heterogeneous nuclear ribonucleoprotein K isoform 1
NM_001301341.1 NP_001288270.1 heterogeneous nuclear ribonucleoprotein K isoform 1
NM_001301343.1 NP_001288272.1 heterogeneous nuclear ribonucleoprotein K isoform 1
NM_001301344.1 NP_001288273.1 heterogeneous nuclear ribonucleoprotein K isoform 3
NM_001301345.1 NP_001288274.1 heterogeneous nuclear ribonucleoprotein K isoform 4
NM_001360490.1 NP_001347419.1 heterogeneous nuclear ribonucleoprotein K isoform 2
NM_001360491.1 NP_001347420.1 heterogeneous nuclear ribonucleoprotein K isoform 5
NM_001360493.1 NP_001347422.1 heterogeneous nuclear ribonucleoprotein K isoform 6
NM_001360494.1 NP_001347423.1 heterogeneous nuclear ribonucleoprotein K isoform 3
NM_001360495.1 NP_001347424.1 heterogeneous nuclear ribonucleoprotein K isoform 4
NM_025279.3 NP_079555.1 heterogeneous nuclear ribonucleoprotein K isoform 2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables RNA binding IDA
IDA: 通过直接分析推断
20548952 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
9185665 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within negative regulation of mRNA splicing, via spliceosome IMP
IMP: 通过突变表型推断
23636947 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IGI
IGI: 通过遗传相互作用推断
24530304 MGI
acts upstream of or within regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator IMP
IMP: 通过突变表型推断
20673990 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasmic stress granule IDA
IDA: 通过直接分析推断
27430620 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

heterogeneous nuclear ribonucleoprotein K

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-135691 hnRNPK-IN-1 97.0% 否
HY-RS06273 HNRNPK Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS21137 Hnrnpk Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS27655 Hnrnpk Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Hnrnpk NCBI NCBI:3190
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