1. Gene
  2. CAMSAP1 - calmodulin regulated spectrin associated protein 1 Gene

CAMSAP1 - calmodulin regulated spectrin associated protein 1 Gene

中文名称:钙调蛋白调节血影蛋白相关蛋白 1

种属: Homo sapiens

基因 ID: 157922 | 基因类型: protein coding

关于 CAMSAP1

Cytogenetic location: 9q34.3 Genomic coordinates (GRCh38): 9:135,808,487-135,907,546 (from NCBI)

This gene has 10 transcripts (splice variants), 280 orthologues and 2 paralogues. Broad expression in testis (RPKM 12.5), brain (RPKM 9.1) and 25 other tissues.

功能概要

启用微管负端结合活性和血影蛋白结合活性。参与多个过程,包括神经元投射发育;细胞形态发生的调节;和微管聚合的调节。位于微管中。与微管负端共定位。 [由基因组资源联盟提供,2022 年 4 月]

Enables microtubule minus-end binding activity and spectrin binding activity. Involved in several processes, including neuron projection development; regulation of cell morphogenesis; and regulation of microtubule polymerization. Located in microtubule. Colocalizes with microtubule minus-end. [provided by Alliance of Genome Resources, Apr 2022]

CAMSAP1 基因产物(2)

mRNA Protein Name
NM_001411031.1 NP_001397960.1 calmodulin-regulated spectrin-associated protein 1 isoform 3
NM_015447.4 NP_056262.3 calmodulin-regulated spectrin-associated protein 1 isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables microtubule binding IDA
IDA: 通过直接分析推断
19508979 GOA
enables microtubule minus-end binding IDA
IDA: 通过直接分析推断
24486153 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
32296183 GOA
enables spectrin binding IDA
IDA: 通过直接分析推断
24117850 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cytoskeleton organization IMP
IMP: 通过突变表型推断
21834987 GOA
involved in microtubule cytoskeleton organization IDA
IDA: 通过直接分析推断
24486153 GOA
involved in neuron projection development IGI
IGI: 通过遗传相互作用推断
24117850 GOA
involved in neuron projection development IMP
IMP: 通过突变表型推断
19508979 GOA
involved in regulation of cell morphogenesis IMP
IMP: 通过突变表型推断
21834987 GOA
involved in regulation of microtubule polymerization IDA
IDA: 通过直接分析推断
24486153 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in microtubule IDA
IDA: 通过直接分析推断
19508979 GOA
colocalizes with microtubule minus-end IDA
IDA: 通过直接分析推断
24486153 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

CAMSAP1 蛋白结构

CH

CH: Calponin homology (CH) domain (186 - 331)

CAMSAP_CKK

CAMSAP_CKK: Microtubule-binding calmodulin-regulated spectrin-associated (1463 - 1582)

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  • 1602 a.a.
蛋白主名 其他名称

calmodulin-regulated spectrin-associated protein 1

epididymis secretory sperm binding protein

直系同源

种属 基因名 来源 基因 ID
Bos taurus CAMSAP1 VGNC VGNC:26730
Macaca mulatta CAMSAP1 VGNC VGNC:70583
Rattus norvegicus CAMSAP1 RGD RGD:1565022
Canis familiaris CAMSAP1 VGNC VGNC:38689
Felis catus CAMSAP1 VGNC VGNC:60341
Mus musculus CAMSAP1 MGD MGI:3036242