2. Gene
  3. EID2 - EP300 interacting inhibitor of differentiation 2 Gene

EID2 - EP300 interacting inhibitor of differentiation 2 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：EP300 相互作用的分化抑制因子 2

种属: Homo sapiens

同用名: CRI2; EID-2

基因 ID: 163126 | 基因类型: protein coding

关于 EID2

Cytogenetic location: 19q13.2 Genomic coordinates (GRCh38): 19:39,538,707-39,540,161 (from NCBI)

This gene has 1 transcript (splice variant), 69 orthologues and 2 paralogues.

功能概要

启用 SMAD 绑定活动。参与多个过程，包括转录负调控、DNA 模板化；转化生长因子β受体信号通路的负调控；和跨膜受体蛋白丝氨酸/苏氨酸激酶信号通路。位于核质中。 [由基因组资源联盟提供，2022 年 4 月]

Enables SMAD binding activity. Involved in several processes, including negative regulation of transcription, DNA-templated; negative regulation of transforming growth factor beta receptor signaling pathway; and transmembrane receptor protein serine/threonine kinase signaling pathway. Located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

EID2 基因产物(1)

mRNA Protein Name
NM_153232.4 NP_694964.3 EP300-interacting inhibitor of differentiation 2
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables SMAD binding IDA
IDA: 通过直接分析推断
14612439 GOA
enables SMAD binding IPI
IPI: 通过物理相互作用推断
14612439 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
15970276 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in negative regulation of SMAD protein signal transduction IDA
IDA: 通过直接分析推断
14612439 GOA
involved in negative regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
14612439 GOA
involved in negative regulation of transforming growth factor beta receptor signaling pathway IDA
IDA: 通过直接分析推断
14612439 GOA
involved in regulation of cell population proliferation IDA
IDA: 通过直接分析推断
14612439 GOA
involved in transforming growth factor beta receptor complex assembly IDA
IDA: 通过直接分析推断
14612439 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

EP300-interacting inhibitor of differentiation 2

CREBBP/EP300 inhibitor 2

关联疾病

疾病名称 别名
Cutaneous Diphtheria

Diphtheria Wound Infection
Siberian Tick Typhus

North Asian Tick Typhus

Manchurian Typhus

North Asian Tick Fever

Rickettsia Sibirica Spotted Fever

Spotted Fever Group Rickettsiosis
Epidemic Pleurodynia

Bornholm Disease

Epidemic Myalgia

Pleurodynia, Epidemic

Devil'S Grip

Bamble Disease

Epidemic Pleurisy

Epidemic, Myositis

Dabney'S Grip

Epidemic Benign Dry Pleurisy

Epidemic Cervical Myalgia
Lymph Node Tuberculosis

King'S Evil

Scrofula

Tuberculous Adenitis

Tuberculous Lymphadenopathy

Tuberculosis, Lymph Node
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS04235 EID2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS18755 Eid2 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS25242 Eid2 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Macaca mulatta EID2 VGNC VGNC:72129
Rattus norvegicus EID2 RGD RGD:1591322
Mus musculus EID2 MGD MGI:2681174
Others EID2 NCBI
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