2. Gene
  3. Itpa - inosine triphosphatase (nucleoside triphosphate pyrophosphatase) Gene

Itpa - inosine triphosphatase (nucleoside triphosphate pyrophosphatase) Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Itp; ITPase; NTPase; 2010016I08Rik

基因 ID: 16434 | 基因类型: protein coding

关于 Itpa

功能概要

Enables dITP diphosphatase activity. Acts upstream of or within ITP catabolic process and chromosome organization. Predicted to be located in cytosol and nucleoplasm. Predicted to be active in cytoplasm. Is expressed in several structures, including alimentary system; genitourinary system; integumental system; nervous system; and sensory organ. Human ortholog(s) of this gene implicated in several diseases, including anemia (multiple); developmental and epileptic encephalopathy 35; hepatitis C; rheumatoid arthritis; and thrombocytopenia. Orthologous to human ITPA (inosine triphosphatase). [provided by Alliance of Genome Resources, Apr 2022]

Itpa 基因产物(2)

mRNA Protein Name
NM_001362648.1 NP_001349577.1 inosine triphosphate pyrophosphatase isoform 2
NM_025922.3 NP_080198.2 inosine triphosphate pyrophosphatase isoform 1
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables dITP diphosphatase activity IMP
IMP: 通过突变表型推断
20081199 MGI
enables nucleoside triphosphate diphosphatase activity IDA
IDA: 通过直接分析推断
1914521 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within ITP catabolic process IMP
IMP: 通过突变表型推断
20081199 MGI
acts upstream of or within chromosome organization IMP
IMP: 通过突变表型推断
20081199 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

inosine triphosphate pyrophosphatase

non-canonical purine NTP pyrophosphatase

non-standard purine NTP pyrophosphatase

nucleoside triphosphate pyrophosphatase

nucleoside-triphosphate diphosphatase

相关产品

Pre-clinical Phase
生物活性分子 (5)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-16965 TH287 Inhibitor 98.99% 否
HY-RS06986 ITPA Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-16965A TH287 hydrochloride Inhibitor / 否
HY-RS20758 Itpa Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS27271 Itpa Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Itpa NCBI NCBI:3704
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