2. Gene
  3. Kcnk2 - potassium channel, subfamily K, member 2 Gene

Kcnk2 - potassium channel, subfamily K, member 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: TREK-1; A430027H14Rik

基因 ID: 16526 | 基因类型: protein coding

关于 Kcnk2

功能概要

Enables voltage-gated Potassium Channel activity. Acts upstream of or within G protein-coupled receptor signaling pathway; potassium ion transport; and regulation of membrane potential. Located in plasma membrane. Part of voltage-gated Potassium Channel complex. Is expressed in several structures, including brain; early conceptus; limb; olfactory epithelium; and secondary oocyte. Orthologous to human KCNK2 (potassium two pore domain channel subfamily K member 2). [provided by Alliance of Genome Resources, Apr 2022]

Kcnk2 基因产物(10)

mRNA Protein Name
NM_001159850.2 NP_001153322.1 potassium channel subfamily K member 2 isoform 1
NM_001281847.2 NP_001268776.1 potassium channel subfamily K member 2 isoform 3
NM_001281848.1 NP_001268777.1 potassium channel subfamily K member 2 isoform 4
NM_001357119.2 NP_001344048.1 potassium channel subfamily K member 2 isoform 4
NM_001402774.1 NP_001389703.1 potassium channel subfamily K member 2 isoform 5
NM_001402775.1 NP_001389704.1 potassium channel subfamily K member 2 isoform 4
NM_001402776.1 NP_001389705.1 potassium channel subfamily K member 2 isoform 4
NM_001402826.1 NP_001389755.1 potassium channel subfamily K member 2 isoform 6
NM_001402827.1 NP_001389756.1 potassium channel subfamily K member 2 isoform 7
NM_010607.4 NP_034737.2 potassium channel subfamily K member 2 isoform 2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables identical protein binding IDA
IDA: 通过直接分析推断
24496152 MGI
enables ligand-gated channel activity IDA
IDA: 通过直接分析推断
23021213 MGI
enables outward rectifier potassium channel activity IDA
IDA: 通过直接分析推断
22726831 MGI
enables potassium ion leak channel activity IDA
IDA: 通过直接分析推断
17110924 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
17110924 MGI
enables protein heterodimerization activity IDA
IDA: 通过直接分析推断
24496152 MGI
enables voltage-gated potassium channel activity IDA
IDA: 通过直接分析推断
11560940 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within G protein-coupled receptor signaling pathway IDA
IDA: 通过直接分析推断
11560940 MGI
involved in chemical synaptic transmission, postsynaptic IDA
IDA: 通过直接分析推断
31728930 MGI
involved in chemical synaptic transmission, postsynaptic IMP
IMP: 通过突变表型推断
31728930 MGI
involved in chloride transmembrane transport IDA
IDA: 通过直接分析推断
23021213 MGI
involved in glutamate secretion IDA
IDA: 通过直接分析推断
23021213 MGI
involved in neuronal action potential IDA
IDA: 通过直接分析推断
22726831 MGI
acts upstream of or within potassium ion transport IDA
IDA: 通过直接分析推断
11560940 MGI
acts upstream of or within regulation of membrane potential IGI
IGI: 通过遗传相互作用推断
22354168 MGI
involved in regulation of synaptic transmission, GABAergic IDA
IDA: 通过直接分析推断
22726831 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
is active in Schaffer collateral - CA1 synapse IDA
IDA: 通过直接分析推断
31728930 MGI
is active in Schaffer collateral - CA1 synapse IMP
IMP: 通过突变表型推断
31728930 MGI
located in astrocyte projection IDA
IDA: 通过直接分析推断
23021213 MGI
located in dendrite IDA
IDA: 通过直接分析推断
17110924 MGI
located in plasma membrane IDA
IDA: 通过直接分析推断
22354168 MGI
part of voltage-gated potassium channel complex IDA
IDA: 通过直接分析推断
11560940 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

potassium channel subfamily K member 2

TREK-1 K(+) channel subunit

outward rectifying potassium channel protein TREK-1

two pore potassium channel TPKC1

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-B1500 2,2,2-Trichloroethanol Agonist 99.53% 否
HY-RS07158 KCNK2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS18069 Kcnk2 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24544 Kcnk2 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Kcnk2 NCBI NCBI:3776
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