1. Gene
  2. Cdc25a - cell division cycle 25A Gene

Cdc25a - cell division cycle 25A Gene

种属: Rattus norvegicus

基因 ID: 171102 | 基因类型: protein coding

关于 Cdc25a

功能概要

Enables phosphoprotein Phosphatase activity. Involved in G1/S transition of mitotic cell cycle and positive regulation of cholangiocyte proliferation. Located in cytoplasm and nucleus. Used to study autosomal recessive polycystic kidney disease. Biomarker of autosomal recessive polycystic kidney disease. Human ortholog(s) of this gene implicated in cervical cancer; prostate cancer; and urinary bladder Cancer. Orthologous to human CDC25A (cell division cycle 25A). [provided by Alliance of Genome Resources, Apr 2022]

Cdc25a 基因产物(1)

mRNA Protein Name
NM_133571.2 NP_598255.2 M-phase inducer phosphatase 1
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables phosphoprotein phosphatase activity IDA
IDA: 通过直接分析推断
10373478 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in G1/S transition of mitotic cell cycle IMP
IMP: 通过突变表型推断
8156993 RGD
involved in positive regulation of cholangiocyte proliferation IMP
IMP: 通过突变表型推断
22155366 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

M-phase inducer phosphatase 1

dual specificity phosphatase Cdc25A

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Cdc25a NCBI NCBI:993