2. Gene
  3. Mid1 - midline 1 Gene

Mid1 - midline 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Fxy; 61B3-R; Trim18; DXHXS1141

基因 ID: 17318 | 基因类型: protein coding

关于 Mid1

功能概要

Predicted to enable several functions, including microtubule binding activity; protein homodimerization activity; and ubiquitin protein Ligase binding activity. Acts upstream of or within negative regulation of microtubule depolymerization. Located in cytoplasm and microtubule Cytoskeleton. Is expressed in several structures, including 1st branchial arch; alimentary system; brain; genitourinary system; and sensory organ. Used to study Opitz-GBBB syndrome and microphthalmia. Human ortholog(s) of this gene implicated in Opitz GBBB syndrome type I. Orthologous to human MID1 (midline 1). [provided by Alliance of Genome Resources, Apr 2022]

Mid1 基因产物(5)

mRNA Protein Name
NM_001290504.1 NP_001277433.1 E3 ubiquitin-protein ligase Midline-1 isoform 2
NM_001290505.1 NP_001277434.1 E3 ubiquitin-protein ligase Midline-1 isoform 2
NM_001290506.1 NP_001277435.1 E3 ubiquitin-protein ligase Midline-1 isoform 3
NM_001290512.1 NP_001277441.1 E3 ubiquitin-protein ligase Midline-1 isoform 4
NM_010797.3 NP_034927.2 E3 ubiquitin-protein ligase Midline-1 isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
15070402 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within negative regulation of microtubule depolymerization IGI
IGI: 通过遗传相互作用推断
15070402 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
15070402 MGI
located in microtubule cytoskeleton IDA
IDA: 通过直接分析推断
15070402 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

E3 ubiquitin-protein ligase Midline-1

RING finger protein Midline-1

RING-type E3 ubiquitin transferase Midline-1

midin

tripartite motif-containing protein 18

相关产品

Clinical Phase
生物活性分子 (1)
目录号 产品名 作用方式
纯度 Phase
HY-115461 MID-1 Inhibitor 99.36% Phase 2
Pre-clinical Phase
生物活性分子 (8)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS08434 MID1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS08435 MID1IP1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS08611 MPG Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS18738 Mpg Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS18951 Mid1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS19281 Mid1ip1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS25441 Mid1 Rat Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS25771 Mid1ip1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Mid1 NCBI NCBI:4281
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