1. Gene
  2. Pias2 - protein inhibitor of activated STAT 2 Gene

Pias2 - protein inhibitor of activated STAT 2 Gene

种属: Mus musculus

同用名: DIP; Dib; Miz1; SIZ2; ARIP3; PIASxb; PIASxbeta; PIASxalpha; PIASxalpha6

基因 ID: 17344 | 基因类型: protein coding

关于 Pias2

功能概要

Enables DNA binding activity; SUMO transferase activity; and ubiquitin protein Ligase binding activity. Acts upstream of or within several processes, including protein sumoylation; regulation of osteoblast differentiation; and transcription, DNA-templated. Located in nuclear body. Is expressed in several structures, including branchial arch; central nervous system; early conceptus; embryo mesenchyme; and genitourinary system. Orthologous to human PIAS2 (protein inhibitor of activated STAT 2). [provided by Alliance of Genome Resources, Apr 2022]

Pias2 基因产物(5)

mRNA Protein Name
NM_001164167.1 NP_001157639.1 E3 SUMO-protein ligase PIAS2 isoform 2
NM_001164168.1 NP_001157640.1 E3 SUMO-protein ligase PIAS2 isoform 3
NM_001164169.1 NP_001157641.1 E3 SUMO-protein ligase PIAS2 isoform 4
NM_001164170.1 NP_001157642.1 E3 SUMO-protein ligase PIAS2 isoform 5
NM_008602.4 NP_032628.3 E3 SUMO-protein ligase PIAS2 isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables DNA binding IDA
IDA: 通过直接分析推断
9256341 MGI
enables RNA polymerase II-specific DNA-binding transcription factor binding IPI
IPI: 通过物理相互作用推断
20408817 MGI
enables SUMO transferase activity EXP
EXP: 通过实验结果推断
15123625 MGI
enables SUMO transferase activity IDA
IDA: 通过直接分析推断
15767674 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
11104669 MGI
enables ubiquitin protein ligase binding IPI
IPI: 通过物理相互作用推断
16816390 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within DNA-templated transcription IDA
IDA: 通过直接分析推断
9256341 MGI
acts upstream of or within protein sumoylation IDA
IDA: 通过直接分析推断
15767674 MGI
acts upstream of or within regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
9256341 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in nucleus IDA
IDA: 通过直接分析推断
16522640 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

E3 SUMO-protein ligase PIAS2

DAB2-interacting protein

Msx-interacting-zinc finger

RING-type E3 ubiquitin transferase PIAS2

androgen receptor-interacting protein 3

msx-interacting zinc finger protein

protein inhibitor of activated STAT x

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Pias2 NCBI NCBI:9063