2. Gene
  3. Mpeg1 - macrophage expressed gene 1 Gene

Mpeg1 - macrophage expressed gene 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: P-2; MPS1; Mpg-1

基因 ID: 17476 | 基因类型: protein coding

关于 Mpeg1

功能概要

Involved in defense response to Gram-negative bacterium; defense response to Gram-positive bacterium; and pore formation in membrane of Other organism. Located in phagocytic vesicle. Is expressed in several structures, including blood vessel; central nervous system; developing vasculature of reproductive system; and retina outer nuclear layer. Human ortholog(s) of this gene implicated in primary immunodeficiency disease. Orthologous to human MPEG1 (macrophage expressed 1). [provided by Alliance of Genome Resources, Apr 2022]

Mpeg1 基因产物(2)

mRNA Protein Name
NM_001374668.1 NP_001361597.1 macrophage-expressed gene 1 protein precursor
NM_010821.2 NP_034951.2 macrophage-expressed gene 1 protein precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables pore-forming activity IDA
IDA: 通过直接分析推断
26402460 MGI
enables wide pore channel activity IDA
IDA: 通过直接分析推断
32064340 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
NOT involved in antibacterial innate immune response IMP
IMP: 通过突变表型推断
35471730 MGI
involved in antibacterial innate immune response IMP
IMP: 通过突变表型推断
26402460 MGI
involved in antigen processing and presentation of exogenous peptide antigen IDA
IDA: 通过直接分析推断
35471730 MGI
involved in antigen processing and presentation of exogenous peptide antigen via MHC class I IDA
IDA: 通过直接分析推断
37347855 MGI
involved in defense response to Gram-negative bacterium IMP
IMP: 通过突变表型推断
23257510 MGI
involved in defense response to Gram-positive bacterium IMP
IMP: 通过突变表型推断
23257510 MGI
involved in defense response to bacterium IMP
IMP: 通过突变表型推断
26402460 MGI
involved in dendritic cell antigen processing and presentation IDA
IDA: 通过直接分析推断
37347855 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasmic vesicle IDA
IDA: 通过直接分析推断
26402460 MGI
is active in endolysosome IDA
IDA: 通过直接分析推断
35471730 MGI
located in phagocytic vesicle IDA
IDA: 通过直接分析推断
26402460 MGI
is active in phagocytic vesicle membrane IDA
IDA: 通过直接分析推断
37347855 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

macrophage-expressed gene 1 protein

macrophage gene 1 protein

perforin-2

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-114512 m-PEG1-NHS ester 95.0% 否
HY-RS08610 MPEG1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS20991 Mpeg1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS27508 Mpeg1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Mpeg1 NCBI NCBI:219972
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