2. Gene
  3. Mt3 - metallothionein 3 Gene

Mt3 - metallothionein 3 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Mt-3

基因 ID: 17751 | 基因类型: protein coding

关于 Mt3

功能概要

Enables zinc ion binding activity. Involved in several processes, including negative regulation of cell death; regulation of cellular macromolecule biosynthetic process; and transition metal ion homeostasis. Acts upstream of or within cellular metal ion homeostasis and negative regulation of neurogenesis. Located in synaptic vesicle. Is expressed in brain; decidua; ganglia; ventral grey horn; and ventricular layer. Human ortholog(s) of this gene implicated in Alzheimer's disease. Orthologous to human MT3 (metallothionein 3). [provided by Alliance of Genome Resources, Apr 2022]

Mt3 基因产物(1)

mRNA Protein Name
NM_013603.2 NP_038631.1 metallothionein-3
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables metal ion binding IDA
IDA: 通过直接分析推断
12130647 MGI
enables zinc ion binding IDA
IDA: 通过直接分析推断
7931547 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in detoxification of cadmium ion IMP
IMP: 通过突变表型推断
20371971 MGI
involved in energy reserve metabolic process IMP
IMP: 通过突变表型推断
21726645 MGI
acts upstream of or within intracellular monoatomic cation homeostasis IDA
IDA: 通过直接分析推断
12130647 MGI
involved in intracellular zinc ion homeostasis IDA
IDA: 通过直接分析推断
20544854 MGI
involved in intracellular zinc ion homeostasis IMP
IMP: 通过突变表型推断
21726645 MGI
involved in leptin-mediated signaling pathway IMP
IMP: 通过突变表型推断
21726645 MGI
involved in negative regulation of apoptotic process IMP
IMP: 通过突变表型推断
19635467 MGI
acts upstream of or within negative regulation of neurogenesis IDA
IDA: 通过直接分析推断
12130647 MGI
involved in negative regulation of neuron apoptotic process IDA
IDA: 通过直接分析推断
21359432 MGI
involved in positive regulation of DNA-templated transcription IMP
IMP: 通过突变表型推断
21726645 MGI
involved in positive regulation of ERK1 and ERK2 cascade IMP
IMP: 通过突变表型推断
21726645 MGI
involved in positive regulation of oxygen metabolic process IMP
IMP: 通过突变表型推断
21726645 MGI
involved in regulation of response to food IMP
IMP: 通过突变表型推断
21726645 MGI
involved in response to oxidative stress IMP
IMP: 通过突变表型推断
19635467 MGI
involved in sequestering of metal ion IMP
IMP: 通过突变表型推断
20371971 MGI
involved in zinc ion transport IDA
IDA: 通过直接分析推断
21359432 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in synaptic vesicle IDA
IDA: 通过直接分析推断
7931547 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

metallothionein-3

GIF

MT-III

growth inhibitory factor

metallothionein-III

相关产品

Pre-clinical Phase
生物活性分子 (6)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-128206 I3MT-3 Inhibitor 99.76% 否
HY-P5846 Muscarinic toxin 3 Antagonist / 否
HY-RS08744 MT3 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-101303 5-MCA-NAT Agonist / 否
HY-RS19565 Mt3 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS26061 Mt3 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Mt3 NCBI NCBI:4504
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